1.0 Introduction The success of Mycobacterium tuberculosis (M. tuberculosis) lies in its ability to persist within humans for longer periods without causing any disease symptoms known as latent infection (LTBI). About 2 billion people are estimated to be latently infected and might reactivate into active TB disease (Kasprowicz et al., 2011). Because of the huge reservoir of latently infected individuals, diagnosis and treatment of latent TB infection has obtained increasing importance as a public
Tuberculosis Tuberculosis is a bacterial infection that is spread through the air. As there is with any other disease, Tuberculosis, or TB, has its telltale signs and symptoms. One symptom with TB is a cough that lasts more than three weeks. TB also causes the person to cough up blood. Chest pain, or pain while breathing or coughing is another symptom of TB. If you have unintentional weight loss, you should see a doctor because you may have TB or a gastrointestinal disease. The usual fatigue
Tuberculosis, an airborne disease, infects people through inhalation of mycobacterium tuberculosis, which is called droplet infection, and is potentially fatal to its victims. (Muller, 2011). Mycobacterium tuberculosis is the causative agent for tuberculosis. There are 19 registered types of mycobacterium that are associated with tuberculosis, which are identified and differentiated by culture of the organism and the disease kills around 1.7 million people each year. Tuberculosis is primarily
Tuberculosis, the white plague as used to be called once upon a time is still one of the deadliest bacterial killers affecting almost all parts, all corners of the globe. Though successful anti-tubercular antibiotic regimens and effective vaccine are available for decades and being used in the battle against Koch’s bacillus, Mycobacterium tuberculosis, the causative agent of this chronic multi organ granulomatous disease, our strand in the battle continuously seems to be in the losing side. Moreover
Introduction Tuberculosis is among the fatal diseases that are spread through the air. It’s contagious, meaning that it spreads from one infected individual to another, and at times it spreads very fast. In addition to being contagious, the disease is an opportunist infection as it takes advantage of those with weak defense mechanism, and especially the ones with terminal diseases like HIV and AIDS. Tuberculosis is therefore among the major concerns for the World Health Organization due to its
Epidemiology Paper on Tuberculosis Tuberculosis (Mycobacterium tuberculosis), also known as TB, is a disease spread by respiratory inhalation of droplets that contain the bacteria. Tuberculosis is an ancient disease that has been traced back at least 9000 years. In 1882, Dr. Robert Koch was the first physician to describe Mycobacterium tuberculosis as the germ responsible for tuberculosis. However, treatment that was evidenced based was not put into practice until the 20th century. It
Tuberculosis (TB), is a bacteria disease caused by the bacterium Mycocardium Tuberculosis (Brennen, 2003). Tuberculosis is unique in a way that the bacterium is neither gram negative or gram positive (Brennen, 2003). For example, “It is classified as acid-fast Gram-positive bacteria, Gram-positive bacteria being the kind that usually cause disease in humans. Mycobacterium tuberculosis is a bacillus or rod shaped bacteria. It has a unique and lipid cell wall that is composed primarily of mycolic acid
TUBERCULOSIS This is a disease that has seen its prevalence not only in developing countries but also in developed nations. It has such a detrimental effect that it has an increased rate on mortality and its the leading cause of death in people with HIV. A report by CDC (2015) states that in 2014 a third of the world was infected by the disease, 9.6 million people around the world were diagnosed with TB disease with 1.5 million deaths worldwide. Definition TB is a contagious and often severe
Introduction For many people in the U.S. tuberculosis represents a disease process that one rarely sees. For this reason the reality of tuberculosis outside of the U.S. can easily be lost. CDC statistics report that approximately one third of the world 's population is infected with tuberculosis.1 This can be a sobering statistic for an individual wholly removed from the idea that tuberculosis, abbreviated TB, remains a prominent disease process throughout much of the world. The objective will
the human body in many forms and varieties. Tuberculosis is one type of these infectious diseases that is a bacterial infection which spreads throughout the lymph nodes and within the bloodstream enabling it to affect all organs in the human body, commonly termed TB. TB is caused by the members of the Mycobacterium tuberculosis complex. The M. tuberculosis complex includes the species M. africanum, M. bovis, M. canettii, M. microti and M. tuberculosis, these can be broken up into numerous subspecies