Osteoclast

The natural process of healing a fracture starts when the injured bone and surrounding tissues bleed, forming a fracture hematoma. The blood coagulates to form a blood clot situated between the broken fragments. Within a few days, blood vessels grow into the jelly-like matrix of the blood clot. The new blood vessels bring phagocytes to the area, which gradually remove the non-viable material. The blood vessels also bring fibroblasts in the walls of the vessels and these multiply and produce collagen

.2 Lytic (erosive) Lytic conditions involve the loss of bone (Byers, 2010). Osteoporosis and rheumatoid arthritis are both common forms of arthritis. Arthritis is a highly prevalent disease that affects 8.5 million people in the UK and almost a quarter of doctor’s visits regard this illness. Osteoporosis causes disproportionate bone loss and inadequate bone replacement. The bone loss causes weakness, so osteoporosis often causes fractures in the vertebral column, femur and radius. Osteoporosis

What is the most likely genetic disease that this presents and why? A. Osteogenesis Imperfecta This patient is most likely presented with osteogenesis imperfecta. This disease is characterized by a group of genetic disorders that mainly affect the bones, in which the patients have their bones break easily resulting either from mild trauma or no apparent cause. Multiple fractures are commonly seen, and in severe cases, can occur even before birth. In milder cases only a few fractures may be seen

Hierarchical architecture and mechanical properties of the various constituents of the bone are important to understand the origin of toughness and stiffness and their alterations with age and disease. 3.1. Macrostructure: cortical and cancellous bone At the macrostructural level, bone is divided into the cortical (or compact) and cancellous (or trabecular) types based upon their degree of porosity or density. Histologically, it is composed of a cortical bone wrapped around older cancellous bone

Osteomalacia is softening of the bones, typically through a deficiency of vitamin D or calcium. Because of the softness of the bones, bowing defects in weight-bearing parts often result (Bontrager, 2014, p. 223). Osteomalacia is not the same as osteoporosis, another bone disorder that also can lead to bone fractures. Osteomalacia results from a defect in the bone-building process (Mayo Clinic, 2014). There are no early symptoms of osteomalacia, but it can be detected on x-ray in its early stages

Osteoporosis is a medical condition in which bones become brittle and fragile as a result of tissue loss. Causes of osteoporosis include hormonal changes, deficiency of vitamin D, and, most commonly, deficiency of calcium. Bones affected by osteoporosis are easily fractured, and such fracturing most often occurs in the hip, wrist, or spine. Under normal circumstances, bone tissue is constantly being broken down and subsequently replaced by the human body; however, osteoporosis prevents the creation

Fibrodyplasia Ossificans Progressiva is an incapacitating disease that affects the connective tissue in the Muscular system. In a normal subject, tendons that connect muscle to bone and ligaments that connect bone to bone help support and cushion the movement of a person’s action. In Fibrodysplasia Ossificans Progressiva the subject’s tendons and ligaments are constricted by the growth of new bone or even replaced over time. “Specifically, this disorder causes the body's skeletal muscles and soft

Trevor disease is a very rare disease that is caused by an asymmetrical limb deformity due to the overgrowth of cartilage. During growth, ossification centers develop individually or together, resulting in bone mass increase. Trevor disease or (DEH) is a rare skeletal developmental disorder characterized by asymmetric overgrowth of cartilage in the epiphyses. Fairbank renamed Trevor disease as DEH. Another name for it is Dysplasia epiphysealis Hemimelica, or (DEH) This disease takes place mostly

Definition: (According to the medical dictionary) The word osteoporosis literally means "porous (sponge-like) bones." It occurs when bones lose an excessive amount of their protein and mineral content, particularly calcium. Over time, bone mass, and therefore bone strength, is decreased. As a result, bones become fragile and break easily. Even a sneeze or a sudden movement may be enough to break a bone in someone with severe osteoporosis. Cause and Symptoms: A number of factors increase the risk

The Effect of Physical Activity on Osteoporosis Jane Tien Thuy Nguyen The University of Iowa October 10, 2014   The Effect of Physical Activity on Osteoporosis According to Kohl & Murray (2012), osteoporosis is defined as a musculoskeletal disorder that results in “low bone mass and structural deterioration of bone tissue” due to “low physical activity levels”, which increases the risk of bone fractures (p.118). Low bone mineral density (BMD) causes bones—most commonly in the hip, vertebrae, wrist