Solvent

distinguish the best way to select the solvent required to recrystallize the solute. Removing the solid impurities of an organic compound involves a series of steps. The first step is to dissolve the solid in the minimum amount of the appropriate hot solvent. Crystallization takes advantage of the fact that most solids are more soluble in a hot than in a cold solvent. We need a solute that is soluble in

The present study was carried out to evaluate the antimicrobial and antioxidant activities of leaves of Elephantopus scaber by using different solvent (ethyl alcohol ,acetone and aqueous). The leaves extract from Elephantopus scaber using different solvents to extract were evaluated for antioxidant activity by using DPPH method using a different concentrations (1, 10, 20, 30, 40, 60, 80, 100) μg/ml. The results of this method was compared with ascorbic acid as standard. The IC50 value of standard

recrystallization. This was done in a couple steps, first dissolved the product to be recrystallized in hot solvent then filtered off impurities, then filtered to isolate the crystals from the recrystallizing solvent [1]. For this method to work there were many different theories that play a role, one of the theories is solubility. Solubility is a chemical property that a solute is able to dissolve in a solvent [2]. This plays a huge role in the experiment as the first step was to dissolve the crude benzoic

this technique is used to dissolve mixture solid in a solvent at high temperature. The solution is then cooled until one of the compounds crystalizes. Extraction technique also cannot be used to separate these two compounds because of the same property they have: they are nonpolar, resulting non acid-base extraction. Extraction technique is used to separate two different compounds to organic and aqueous layer, which means one phase of one solvent has to be polar and the other phase has to be nonpolar

liquid-solid extraction is used when adding a solvent to a solid. Therefore, the proper technique for this lab that was used was the liquid-liquid extraction and recrystallization technique. The two solvents that were used was the original mixture that was initially discovered and the extraction which is used to pull out one of the mixtures from the liquid. The extraction solvent and the original mixture must be immiscible with one another. The extraction solvent must be able to reversibly

Calculation of the number of equilibrium stages required, had to be done using a Ternary Diagram (Figure 4). Equilibrium data was provided that could be plotted (Table A3); however, an average of the component mol% for the Raffinate, Extract Feed and Solvent streams had to be determined. This required the conversion the experimental data of the normalized volume percent (vol%) in Table A1 into mol% values, so the data points could be plotted on the Ternary Triangular Diagram. Conversion from vol% to mol%

to be entrapped in microsponge drug delivery system. Formulation of resiquimod loaded microsponges was done using oil in water emulsion solvent evaporation method. The method had two phases, organic and aqueous phase. Three types of solvent were used in organic phase along with four volumes. Dichloromethane (DCM), chloroform and ethyl acetate (EA) were the solvent in organic phase with the volumes were used 1, 2.5, 5, 10 mL. Different formulations

vital one. This is due to its effectiveness, convenience, and industrial applications. Recrystallization has to do with dissolving organic compounds to purify them. The solid acts as the solute as it dissolves in an appropriately selected hot solvent. The solvent is then cooled which allows for the solution to become saturated with the solute. This leads to recrystallization,

easily breaks apart in a polar solvent meanwhile, sodium chloride is not soluble in hexane because of the structure and polarity of hexane that is non-polar. Thus, when NaCl is put into hexane, the charged particles and the non-polar particles would stay altogether resulting in no mixing or dissolution. Naphthalene is non-polar covalent solute therefore it dissolves in non-polar solvent (hexane) and it will not be able to dissolve in water, which is polar solvent. Citric acid and sodium bicarbonate

Description Parts of solvent needed for one part of solute Very soluble 10000 Approaches to Increase solubility/ Dissolution: Various techniques have been used in attempt to improve solubility and dissolution rates of poorly water soluble drugs which include solid dispersion, micronization, lipid based formulations, melt granulation, direct compaction, solvent evaporation, co precipitation, adsorption, ordered mixing, liquisolid compacts, solvent deposition inclusion complexation and steam aided