b2900 lab 3 popn genet PRE-LAB w24 yrt WORD

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University of Notre Dame *

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Feb 20, 2024

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B2900 L3: Population Genetics Pre-lab (Winter 2024) 1 Biology 2900 Lab 3: Population Genetics Pre-Lab Value: 5% of your total b2900 mark [pre-lab is worth 1.5% (marked out of 2, lab is worth 3.5% (marked out of 11)] Assignment: this file (with completed questions) uploaded to the brightspace lab 3 pre-lab assignment folder Due: PRIOR to lab 3 Please complete the pre-lab questions and upload to brightspace before coming to lab. Suggested readings: (From Evolution 4 th Edition by Futuyma and Kirkpatrick – available on brightspace) Natural Selection (pg. 59) Natural Selection and chance (pg. 61) The inheritance of variation (pg. 82) Gene mixing by segregation (Hardy-Weinberg equilibrium, pg. 83) Overdominance (pg. 121) Genetic drift (pg. 166) Figure 7.3 (pg 169) Genetic Divergence between populations (FST statistic, pg. 196) B2900 L 3 Prelab: Population Genetics Complete using information from text and lectures before coming to the lab (0.5) 1. Define recessive alleles and deleterious alleles. Can a single allele be one, both or none of these types? (0.25) 2. What is “overdominance” ? (0.25) 3. What is genetic drift? (0.75) 4. Given p = 0.9 for an A 1 allele, and q = 0.1 for an A 2 allele, calculate the genotype frequencies in a population. When an allele frequency is low (the A 2 allele in this case), are most of the alleles in heterozygous individuals or homozygous individuals within the population? When an allele frequency is high (the A 1 in this case), are most of the alleles in heterozygous individu- als or homozygous individuals? 1
B2900 L3: Population Genetics Pre-lab (Winter 2024) 2 (0.25) 5. What does the F ST statistic measure? 2
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