2PHGY216_AppliedPhysiology
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Queens University *
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Course
216
Subject
Biology
Date
Apr 3, 2024
Type
Pages
2
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Questions
1.
Exploring LF’s lung function:
a.
Use the provided spirometry test results in Table 1 to calculate the change in pre- vs
postbronchodilator function for FEV1, FVC, and FEV1/FVC ratio. Present your results
both
as values in litres and as percent-change.
(These values are to be presented in a Table
that does
not
count towards the word count of this question.)
b.
What do the above values tell you about LF’s condition?
c.
Using your knowledge of respiratory physiology, describe
how
use of a bronchodilator
explains the test results observed.
2.
Once LF is stable, you find out he was born prematurely. Prematurity is often associated with
surfactant deficiency. How might a lack of surfactant impact on pulmonary function?
3.
Use the values in Table 3 to graph the following two graphs:
a.
LF’s lung function trajectory over 30 days. Use the figure caption to briefly describe any
trends you observe.
b.
Calculate and graph LF’s ‘weekly average’ PEFR values (
where ‘week’ in this context
means 5 days
). Use the figure caption to briefly describe any trends you observe.
c.
…
then briefly speculate on one plausible explanation for the trends you are observing
(i.e., what is something that might have caused what you are seeing?)
4.
Based on the case values provided, describe the acid-base milieu that LF is experiencing (a) at
the start of his hospital admission and (b) at the end of the 12-h period provided, if different
from the milieu at the start. What methods of compensation would be possible for this milieu
and
how
would these happen? Justify and describe your reasoning by applying your knowledge.
5.
Using the “MDRD” (
Modification of Diet in Renal Disease
) equation for estimating glomerular
filtration, provided below, and the data available in Table 3, calculate LF’s estimated glomerular
filtration rate (eGFR) at admission and 12h after admission.
MDRD GFR Equation (mL/min/1.73 m
2
)
=
175 × (S
cr
)
-1.154
× (Age)
-0.203
× (0.742 if female) × (1.212 if African American)
Based on your calculated values, state whether LF’s function is normal or abnormal?
Previous research suggests that patients with asthma have an increased risk for chronic kidney
disease, but the mechanisms underlying this increased risk are poorly understood. Integrate
your knowledge of renal function as gleaned from your module to propose one potential
mechanism by which asthma might impair kidney function, and discuss how this dysfunction
may impair the body’s ability to respond to the acid-base disturbance you have identified in
Question 4.
Points Allocation:
Question 1
(15 pts)
a)
b)
2 pts/calculated answer = 6 pts
9 points written response
Question 2
(15 pts)
15 pts
Question 3
(20 pts)
a)
b)
Graph 1: 6 pts
Graph 2: 9 pts
c)
Written response: 5 pts
Question 4
(15 pts)
10 pts to describe/justify milieu
5 pts to justify type of compensation available
Question 5
(15 pts)
a)
3 pts/calculated answer = 6 pts
b)
9 pts for proposal
Formatting, writing, referencing
(20 pts)
20 pts
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Please review the image below for the questions.
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Match each term in Column I with its function or description in Column II.
COLUMN I
COLUMN II
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a. inspiratory reserve volume
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2. oxidation
c. elular respiration
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4. breathing
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Statement B: Normal expiration results from the elastic recoil of the lungs.
1.Only statement A is correct
2.Only statement B is correct
3.Both statements A and B are correct
4.Both statements A and B are incorrect
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QUESTION 1
Match the number in the image below to the correct structure.
1
2
3
12
11
4
10
6.
9.
8.
7
A. left primary bronchus
B. left lung
C. larynx
D. nares
E. right lung
F. oral cavity
7.
G. pharynx
H. diaphragm
1. trachea
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Jright primary bronchus
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K. epiglottis
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L. nasal cavity
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A 73-year-old man with a long history of smoking demonstrates the following clinical data on a pulmonary function test (PFT):
Based on the information shown, the patient appears to have
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Identify the indicated structures
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Please answer this question
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Could you please help me with my reaction paper.
Make a simple reaction to this. Thank you
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This is NOT graded!
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Use the figure to match the following.
Drag the appropriate labels to their respective targets.
Trachea
Carina of trachea
Pharynx
Main (primary)
bronchus
Larynx
Submit
Request Answer
Right lung
Left lung
Diaphragm
Reset
Help
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20
Volume (mL)
Short answer
Identify and describe the pulmonary volumes and capacities indicated in the spirogram below.
6000
15
16
15
17
19
18
21
19
2700
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16
2200
21
17
1200
22
23
23
22
18
- Time
Section integration
Compare and contrast external respiration, pulmonary ventilation, and internal respiration.
24
notor
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Contraction of the diaphragm increases the volume of the thoracic cavity
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Can Stock Photo - csp8995075
O a 1 and 3
O b. 1 and 4
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4
The detection of rotation of the head and the equalization of air pressure between the external environment and the middle ear are, respectively, function
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Complex
Pasig City, Philippines 1600
Telefax: (632) 638-4799 o 637-4347
E-mail
bcd-csd@deped.gov.ph
B. Put a check mark () if the item shows proper care of the respiratory and circulatory systems,
and a cross mark (*) if not. Write your answers on the blanks.
1. Playing in clean grounds every day
2. Exercising frequently
3. Smoking
4. Getting plenty of rest and sleep
5. Drinking too much alcohol
6. Eating healthy foods
7. Having regular medical checkups
8. Chewing tobacco
9. Eating snacks high in salt, sugar, and fat
10. Keeping a normal weight
C. In each item, encircle the word in the parentheses that best completes the sentence about
keeping your respiratory and circulatory systems healthy.
1. When you exercise, your heartbeat (increases, decreases).
2. The (more, less) fit you are, the better your heart and lungs will work.
3. (A healthy, An unhealthy) diet contains the right balance of foods that can make your
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