Work Sheet_ SI Wania_2023-11-7_Session 10

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University of Massachusetts, Amherst *

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151

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Biology

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Apr 3, 2024

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Biology-151 (Fall 2023) SI Wania Imran ( wimran@umass.edu ) Prof.Mark Huyler Worksheet is intellectual property of UMass Amherst LRC’s SI Program Please Do Not Post Without Permission Practice Exam If True / False (2pts / question) Select A if the statement is TRUE or Select B if the statement is FALSE. For multiple choice questions select the one best answer. Relative to genetics (T/F)... 1. Mendel’s Principle of Independent Assortment states that two members of a gene pair segregate equally into gametes so that half of the gametes get one allele and half of the gametes get the other allele. 2. Thomas Hunt Morgan, working with fruit flies, was the first person to describe X-linked traits. 3. Mendel’s Principal of Segregation states that nonhomologous chromosomes align on the metaphase plate in one of two ways independently from each other. 4. Marfan’s syndrome (an autosomal dominant trait) is an example of “incomplete penetrance”. Coat color in Labrador Retrievers is regulated by a pair of autosomal recessive genes. On one pair of genes Black (“B”) is dominant to chocolate (“b”). Yellow coat color is the result of a recessive epistatic allele (“ee”) that blocks the expression of both the black and chocolate color and produces the yellow color. 5. A yellow male (Bbee) was mated to a black female. If the resulting litter had 8 puppies (4 yellows, 3 blacks, and 1 chocolate) then there is a very high probability that female was heterozygous for both genes. Feel free to use the table below in your deliberations. Consider the following pedigree ....

Biology-151 (Fall 2023) SI Wania Imran ( wimran@umass.edu ) Prof.Mark Huyler Worksheet is intellectual property of UMass Amherst LRC’s SI Program Please Do Not Post Without Permission 6. If this condition were an autosomal recessive trait then the male in generation #1 would have to be homozygous 7. There is a high probability that this is a sex linked trait because there are disproportionally more affected males than females 8. This could be a pedigree of an autosomal dominant trait. 9. It is likely that this pedigree represents an autosomal recessive trait 10. This pedigree could represent an X-linked recessive trait. 11. A “Roan” coat color (C r C w ) in cattle is produced when an animal with a white coat (C w C w ) is crossed with an animal with a red coat (C r C r ). If we crossed two “roan” animals the expected phenotypic frequencies would be: a. 25% Roan / 50% Red / 25% White b. 75% Roan / 25% White c. 25% Red / 25% White / 50% roan d. none of the above

Biology-151 (Fall 2023) SI Wania Imran ( wimran@umass.edu ) Prof.Mark Huyler Worksheet is intellectual property of UMass Amherst LRC’s SI Program Please Do Not Post Without Permission 12. The probability of getting a female roan calf by crossing a red coated female and white coated male would be 50% The following three questions are relative to this example: Hemophilia is an X-linked recessive trait. If a woman (whose mother didn’t have the condition) with hemophilia has a child with a man that doesn’t... 13. The likelihood that their first child will have the disease is 50% 14. Any resulting female offspring would all suffer from this disease while male offspring will be carriers. 15. We immediately know that the mother of the woman above had to be heterozygous for the condition and that her father had to have the affliction. You have conducted extensive experiments studying the inheritance of four genes (A, B, C, D) that are all located on the same chromosome in Drosophlia melanogaster . You have recorded the frequency of recombination in the resulting offspring for each of the following gene pairs: Gene Pair Frequency of Recombination or Map Units A–B 20 A–C 28 A–D 5 16. Given the data above, the order of the genes on the chromosomes would be: A – D – B – C 17. Because “A” and “D” genes are the located the closest together on the chromosome the likelihood of crossing over occurring between the two of them would be the lowest. 18. The distance between B and D would be 15 Map Units

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