Topic: Metastatic Bone Disease
Specific Purpose: My intention is to raise awareness of one cancer as well as understanding the purpose of the study.
Central Idea: Metastatic bone cancer also known as Osteosarcoma is rare cancer that has no cure. For That reason, more funding and research need to go treatment.
Organizational Pattern: Topical order
Developmental Forms: Development, Visual Aids
I. Get attention. I am going to speak to my classmate about cancer. I know cancer is a difficult and scary subject to talk about with anyone. And what is cancer? Cancer is cells that grow out of control while normal healthy cells grow at a steady pace. There is more than one type of cancer, however, a group of related diseases that can …show more content…
2. Patients with a tumor that has spread to the spinal bones possibly will build up nerve damage that can lead to paralysis or loss of the use of the legs and/or arms (Fischer and Quinn, 2011).
3. Fresh bone can form in response to cancer spread osteoblastic, grows abnormally and causes the bone to be weak and deformed (Fischer and Quinn, 2011).
Transition: Now that you are informed about metastatic bone cancer, let’s jump to the funding for this cancer
II. Need more funding for research the fact that MBC kills 40,000 women (and men) every year.
A. Metastatic breast cancer, i.e., cancer that spreads to other parts of the body and eventually causes death. Sadly, these deaths are often overlooked amid all the hot pink fundraising and survivor-focused hoopla (Diane Mapes, 2016).
B. Doesn’t track recurrence or progression. It only counts you when you die of cancer — another sore point for metsters, who feel it’s an “unconscionable” oversight which, among other things, damages their ability to lobby for more research funding. No data, no dollars (Diane Mapes, 2016).
C. From basic research to late phase clinical trials.
Transition: Since we know that funding for this cancer is so low let’s see how far research study goes.
III. The purpose of research is for physicians and scientists with one goal to find a cure.
A. There is Research center that educates new generation of scientist
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As stated by curesearch.org this does not take into consideration the many children who succumb to their cancers after more than 5 years, nor does it account for those struggling with life-threatening effects of their cancer treatment, even including secondary
This cancer is a bone cancer that attack the bones, especially large bones. This cancer is named osteogenic sarcoma(Osteosarcoma) for medical term (“Osteosarcoma”, n.d.). Osteosarcoma mostly affects people under 25 years old, and it can affect old people but it is really rare(“Osteosarcoma: An Introduction.”, 2012). When this cancer attacks, it grows bones, and any type of bone (“Bone cancer”,2013). This cancer is an ancient disease that we started to recognize in 1805. Most of the symptoms are on the bones (“Bone cancer”,2013). It also is not contagious so its not passed from person to person like other diseases.
However, with medicine advancing, we are able to understand osteosarcoma a little better. Recent studies in the past couple of months have looked at cadavers with osteosarcoma, thanks to patients who have donated their bodies to science. Upon this research they found many new discoveries, such as the direction it tends to grow and where the cancer is most likely to spread. The advancement of medicine found out that the most common way to die from osteosarcoma was pulmonary metastatic disease. This disease is caused from cancer cells spreading to the lungs.When the cancer from the osteosarcoma spreads throughout the body, it often ends up in the lungs, which then begins the vicious stages of lung cancer. Symptoms of osteosarcoma include pain and swelling, usually around the upper arm or knee, and bones that are easily fractured. The bones tend to fracture very easily where the osteosarcoma is
Osteosarcoma(OS) is a primary malignant tumor of bone which is characterized by the formation of osteoid tissue. Although it is the most common malignancy of long bones after multiple myeloma , it is a relatively rarer entity in the craniofacial region. About 6% of Oss arise in the jaws .The estimated incidence of the new cases of Jaw OS (JOS) per year is 0 .07 in 100,000. (1) The etiology of OS is unknown, but some risk factors such as a previous history of ionizing radiation, alkylating agent, retinoblastoma and benign bone lesions such as paget disease and fibro osseous dysplasia have been associated with the development of head and neck OS.(2-4) JOS occur with a peak in the third through fifth decades of life. The mean age is
Imagine if every time your knee was sore, or your arm was sore, you had to go see the doctors. This commonly happens to children, and adults who are diagnosed with Osteosarcoma. Since Osteosarcoma is a bone tumor/cancer, the symptoms and treatment have an impact on everyday life.
In summary, this research has the potential to improve the quality of life for Medicare beneficiaries through decreases of side effects, improved convenience, decreased time receiving treatment and reduction in economic hardship. Single-fraction treatments decrease cost to the patient and decrease the number of treatments and resources needed. In addition, Medicare providers will benefit through the education of effective treatment modalities for their metastatic bone cancer
There are 206 bones in the adult human skeleton; these bones relate to movement, posture, and protect internal organs (American society of Clinical Oncology, 2012).Bones connect to bones with ligaments and are covered and protected by cartilage (American Society of Clinical Oncology, 2012).Cancer of the bone is rare but is caused by normal bone marrow and tissues inside the bone that change and form tumors(American Society of Clinical Oncology, 2012). The tumor happens in the bone and is benign it does not spread (American Society of Clinical Oncology, 2012). The benign tumor can press against surrounding tissues and weaken the bone it it grows big enough (American Society of Clinical Oncology, 2012). Malignant bone tumors break the surrounding tissue and cortex, hard covering of the bone (American Society of Clinical Oncology, 2012). The tumor can then get into the bloodstream and spread all over the body (American Society of Clinical Oncology, 2012). Osteosarcoma and ewing sarcoma are the two most common type of bone cancer (American Society of Clinical Oncology, 2012). Chondrosarcoma is more common in adults and is cancer of the cartilage (American Society of Clinical Oncology, 2012). The last type of bone cancer is chordoma which usually starts in the lower spinal cord (American Society of Clinical Oncology, 2012). Ewing sarcoma is a type of bone cancer that affects the hip, rib, and middle of bone most often (National Cancer Institution, 2015). Ewing
Just last year, when I come across this heartbreaking story about a young mother Kaley Fitzsimmons. As an sport instructor and a mother of a young beautiful daughter, Ms. Fitzsimmons dreams is to be there to watch her daughter grow up. But after 9 months fighting Osteosarcoma, a common type of bone cancer that found in growing bones, she has peacefully passed away on July 15, 2015, according to Daily Mail, a news from UK. Additionally, On July 17, 2015, in Medical News Today, a health information site I learned that cancer is the second most common cause of death in America with 14 million new cancer cases and 8.2 million cancer-related deaths in 2012 according to their most recent data.
American Cancer Society (2014) states that osteosarcoma is a rare cancer that starts primarily in the bone. According to the American Cancer Society (2014), annually, about 800 people are newly diagnosed with osteosarcoma in the United States of America. Among the newly diagnosed cases, 400 are children and teenagers. Osteosarcoma is usually observed in children, adolescents and adults ages 10 to30. Of the three mentioned, teenagers are mostly affected, nonetheless osteosarcoma can happen at any stage. Osteosarcoma usually begins in the legs, close to the end of the long bones primarily targeting the knee. Another commonplace for osteosarcoma to be present is near the
Osteosarcomas are primary malignant tumors of the bone characterized by the production of osteoid or immature bone by malignant cells. Although uncommon in general, they are the most common primary malignancy of bone in children and adolescents, and the fifth most common malignancy among adolescents and young adults age 15–19 years old. There is a bimodal age distribution of osteosarcoma incidence, with peaks in early adolescence and in adults over the age of 65. In children, the majority of cases are sporadic, while in older adults, about one third of the cases arise in the setting of Paget disease of the bone. Risk factors include prior irradiation or chemotherapy, Paget disease and other benign bone lesions, and inherited conditions. The majority of patients with osteosarcoma present with localized pain over several months’ duration. The pain commonly begins after an injury and may wax and wane over time. The most important finding on physical examination is a soft tissue mass, which may be large and tender to palpation. Osteosarcomas are commonly found in the metaphyseal region of the long bones, most commonly the distal femur and proximal tibia. Laboratory evaluation may find elevations in alkaline phosphatase, lactate dehydrogenase (LDH), and erythrocyte sedimentation rate. Characteristic features found on plain radiographs include destruction of the normal trabecular bone pattern, indistinct margins, and lack of endosteal bone
In this paper, Osteosarcoma will be taken apart by details. The symptoms, treatment, signs, and other details will be discussed and explained. In a normal bone for most people there are two types of cells; osteoblasts and osteoclasts. Osteoblasts are what build up our bones by forming the bone matrix and therefore gives us the strength in our bones. Osteoclasts on the other hand break down the bone matrix so that we don’t get too much of it and that helps the bones to keep its proper shape. In Osteosarcoma the osteoblasts are what help make up the cancer in the bones. The bones do not have as strong of a bone matrix. This type of cancer is most commonly found in kids and young adults. There are three forms of treatment but not
Each day, hundreds of people find themselves face to face with the word “cancer.” There is an estimate of 4600 new cancer diagnosis each day. Cancer is the second leading cause of death in the united states, and is a major health concern worldwide. However, over the past 3 decades the survival rate for all cancers has climbed over 20%.
Malignant bone tumors have a propensity to spread via the bloodstream to various areas of the body, especially to the lungs and other bones. Annually, approximately 2800 new bone sarcomas are diagnosed in the United States. Unlike soft tissue tumors, malignant bone tumors present most commonly with pain. Therefore, these tumors require serious therapy plans that typically involve some combination of surgery, chemotherapy, and bone reconstruction. Specifically, the treatment of a malignant tumor calls for resection of the main tumor as well as the normal tissue surrounding the cancerous area. Bone sarcomas can come in three types: Osteosarcoma, Ewing sarcoma, and Chondrosarcoma.