1. Draw the peptide HSK below at pH 7 and give its overall charge at pH 2, 7, and 12:

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
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Chapter9: Parenteral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 6.4P
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Amino Acid pka Values
Amino Acid
a-carboxylic
acid
Alanine
2.35
Arginine
2.01
Asparagine
2.02
Aspartic Acid 2.10
Cysteine
2.05
Glutamic Acid
2.10
Glutamine
2.17
2.35
1.77
2.32
2.33
2.18
Glycine
Histidine
Isoleucine
Leucine
Lysine
Methionine
Phenylalanine
Proline
Serine
Threonine
Tryptophan
Tyrosine
Valine
2.28
2.58
2.00
2.21
2.09
2.38
2.20
2.29
a-amino
9.87
9.04
8.80
9.82
10.25
9.47
9.13
9.78
9.18
9.76
9.74
8.95
9.21
9.24
10.60
9.15
9.10
9.39
9.11
9.72
Side chain
12.48
3.86
8.00
4.07
6.10
10.53
10.07
1. Draw the peptide HSK below at pH 7 and give its overall charge at pH 2, 7, and 12:
Transcribed Image Text:Amino Acid pka Values Amino Acid a-carboxylic acid Alanine 2.35 Arginine 2.01 Asparagine 2.02 Aspartic Acid 2.10 Cysteine 2.05 Glutamic Acid 2.10 Glutamine 2.17 2.35 1.77 2.32 2.33 2.18 Glycine Histidine Isoleucine Leucine Lysine Methionine Phenylalanine Proline Serine Threonine Tryptophan Tyrosine Valine 2.28 2.58 2.00 2.21 2.09 2.38 2.20 2.29 a-amino 9.87 9.04 8.80 9.82 10.25 9.47 9.13 9.78 9.18 9.76 9.74 8.95 9.21 9.24 10.60 9.15 9.10 9.39 9.11 9.72 Side chain 12.48 3.86 8.00 4.07 6.10 10.53 10.07 1. Draw the peptide HSK below at pH 7 and give its overall charge at pH 2, 7, and 12:
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