4. Compare the DNA sequences of individuals with Alzheimer's disease and their family members. Two codons in the APP gene sequence are different in the two patients with Alzheimer's disease compared to individuals without the disease. Consider the first codon that's different and complete the table below. Codon in Codon in Amino Acid DNA template strand MRNA APP gene in individuals without Alzheimer's disease APP gene in individuals with Alzheimer's disease Does the change in this codon represent a silent or a missense mutation? Explain.

Biology: The Unity and Diversity of Life (MindTap Course List)
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ISBN:9781305073951
Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
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Chapter18: Organizing Information About Species
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4. Compare the DNA sequences of individuals with Alzheimer's disease and their family members. Two codons
in the APP gene sequence are different in the two patients with Alzheimer's disease compared to individuals
without the disease. Consider the first codon that's different and complete the table below.
Codon in
Codon in
Amino Acid
DNA template strand
MRNA
APP gene in individuals
without Alzheimer's
disease
APP gene in individuals
with Alzheimer's disease
Does the change in this codon represent a silent or a missense mutation? Explain.
Transcribed Image Text:4. Compare the DNA sequences of individuals with Alzheimer's disease and their family members. Two codons in the APP gene sequence are different in the two patients with Alzheimer's disease compared to individuals without the disease. Consider the first codon that's different and complete the table below. Codon in Codon in Amino Acid DNA template strand MRNA APP gene in individuals without Alzheimer's disease APP gene in individuals with Alzheimer's disease Does the change in this codon represent a silent or a missense mutation? Explain.
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