Which of the following mRNA codons could be changed to a stop codon by a single base pair substitution in DNA ?  [In other words, if you substitute one of the bases for a diferent one, it will produce a stop codon. Don't overthink this.  Just look at the codon as written, and see if changing any one base leads to a stop codon].   1. UAC (tyrosine) 2. UGG (tryptophan) 3. CGA (arginine) 4. ACU (threonine)   A.  1, 2 and 3   B.  1 and 3   C.  2 and 4   D.  4 only   E. All of 1, 2, 3 and 4 are correct

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
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Author:Michael Cummings
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Chapter11: Genome Alterations: Mutation And Epigenetics
Section: Chapter Questions
Problem 14QP: In the gene-coding sequence shown here, which of the following events will produce a frameshift...
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Which of the following mRNA codons could be changed to a stop codon by a single base pair substitution in DNA ?  [In other words, if you substitute one of the bases for a diferent one, it will produce a stop codon. Don't overthink this.  Just look at the codon as written, and see if changing any one base leads to a stop codon].  

1. UAC (tyrosine)

2. UGG (tryptophan)

3. CGA (arginine)

4. ACU (threonine)

  •  
    A. 

    1, 2 and 3

  •  
    B. 

    1 and 3

  •  
    C. 

    2 and 4

  •  
    D. 

    4 only

  •  
    E. All of 1, 2, 3 and 4 are correct
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