5. Using curved arrows, draw the mechanism of both steps involved in the synthetic pathway to imidazole (5). H;C CH;Co0 NH,* H3C ENH H3C -N HN -H -H H3C- H H;C- `NH H3C- 1 2 4 5 6. Suggest a reasonable retrosynthetic approach to disconnect oxazole (1) and draw the mechanism of the forward Robinson-Gabriel reaction: H3C -N H3C `N- 1 ZI

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter19: Eas: Electrophilic Aromatic Substitution
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Solve Q5 and Q6 with detailed expalantion 

5. Using curved arrows, draw the mechanism of both steps involved in the synthetic
pathway to imidazole (5).
H3C
CH,Co0 NH,*
H3C
ENH
H3C
-N-
HN
-H
H3C
H3C-
`NH
H3C
H
1
2
3
4
5
6. Suggest a reasonable retrosynthetic approach to disconnect oxazole (1) and draw the
mechanism of the forward Robinson-Gabriel reaction:
H3C
-N
H3C
`N-
1
Transcribed Image Text:5. Using curved arrows, draw the mechanism of both steps involved in the synthetic pathway to imidazole (5). H3C CH,Co0 NH,* H3C ENH H3C -N- HN -H H3C H3C- `NH H3C H 1 2 3 4 5 6. Suggest a reasonable retrosynthetic approach to disconnect oxazole (1) and draw the mechanism of the forward Robinson-Gabriel reaction: H3C -N H3C `N- 1
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