6. Identify whether the following proposed reactions would take place readily under mild conditions. Briefly explain why. (a) H;C-8-NH2 -Ci + NANH2 + NaCI H3C- (b) + Ph- CH;NH, Ph-C-NHCH, + HCI (c) (CH)»CH-8-NH, + CH,OH (CH3)2CH–E-oCH, + NH, (d) CH,CH2-C-Cı + H,C-8-OH CH,CH2–&-o-8-CH, HCI (e) + CH3-C-0-č-CH3 CH;NH2 CH3-C-NHCH3 + CH;COOH +

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter13: Substitution
Section: Chapter Questions
Problem 8CTQ
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Kindly answer no 6 d&e

6. Identify whether the following proposed reactions would take place readily under mild
conditions. Briefly explain why.
(a)
H3C-C-NH,
H,C-8-cı
+
NaCI
+
NANH2
(b)
Ph-8-ci
CH;NH2
Ph-C-NHCH, + HCI
(c)
(CH3)2CH-C + CH,OH
H_8-OCH, + NH,
–NH2
(CH3)2CH–C-OCH3
(d)
CH,CH2-C-Cı + H,C_8-OH
CH,CH2-C-0-8-cH,
HCI
(e)
-ě-o-8-cH, +
CH3-
CH3NH,
CH3-C-NHCH3
+
CH;COOH
Transcribed Image Text:6. Identify whether the following proposed reactions would take place readily under mild conditions. Briefly explain why. (a) H3C-C-NH, H,C-8-cı + NaCI + NANH2 (b) Ph-8-ci CH;NH2 Ph-C-NHCH, + HCI (c) (CH3)2CH-C + CH,OH H_8-OCH, + NH, –NH2 (CH3)2CH–C-OCH3 (d) CH,CH2-C-Cı + H,C_8-OH CH,CH2-C-0-8-cH, HCI (e) -ě-o-8-cH, + CH3- CH3NH, CH3-C-NHCH3 + CH;COOH
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