WA82. Regulation of cellular metabolism by insulin requires activation of the insulin-receptor substrate protein-1 (IRS1). Some individuals who have type 2 diabetes mellitus have mutations in theIRS1 gene. Which of the following normal steps in insulin signaling is most likely to be impaired by these mutations?A) Cleavage of IRS1 by the insulin receptorB) Phosphorylation of IRS1 by the insulin receptorC) Production of inositol 1,4,5-trisphosphate by IRS1D) Stimulation of a G protein by IRS1E) Synthesis of diacylglycerol by IRS1

A strong anabolic agent, insulin promotes nutrient uptake, storage, and synthesis within cells while…

Answered: 82. Regulation of cellular metabolism…

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter9: Cell Communication

Section: Chapter Questions

Problem 12RQ: Histamine binds to the H1 G-protein-linked receptor to initiate the itchiness and airway...

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9 Insulin can be best described by which statements? Select the correct response(s): It is made up of 2 peptide chains with a total of 3 alpha helices, 2 beta sheets, and 3 disulfide bridges. It is synthesized by the beta cells of the pancreas and released into the bloodstream to stimulate assimilation of glucose by the cells. It is made up of 2 peptide chains with a total of 3 alpha helices, 2 beta sheets, and 2 disulfide bridges. It is synthesized by the beta cells of the pancreas and released into the bloodstream to stimulate secretion of glucose by the cells. It is synthesized by the beta cells of the pancreas and released into the bloodstream to stimulate synthesis of glucose by the cells. It is synthesized by the beta cells of the pancreas and released into the bloodstream to stimulate oxidation of glucose by the cells. | It is made up of 2 peptide chains with a total of 2 alpha helices, 2 beta sheets, and 2 disulfide bonds. • It is made up of 2 peptide chains with a total of 2…
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