A clinical trial is planned to compare an experimental medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is conducted involving 10 participants. The objective of the study is to assess how systolic blood pressure changes over time untreated. Systolic blood pressures are measured at baseline and again 4 weeks later.

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Q: The

A: Design of experiment

2-Proportion Test

In a 2-proportion test, two separate proportions are measured at the same time, and their similarity is evaluated. It is also known as a 2-proportion z-test, and a comparison of two different proportions is done in this method.