A decrease in blood glucose levels will, in the liver, lead to the inhibition, either directly or indirectly, of which of the following enzymatic activities? Select one: a. Lactate dehydrogenase b. Phosphofructokinase c. Pyruvate kinase d. Enolase
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- Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is inhibited by· NIADH. Pyruvate dehydrogenase is inhibited by AΤΡ. Citrate synthase is inhibited by NADH. Succinyl-CoA activates citrate synthase. Acetyl-CoA activates pyruvate carboxylase.In the last step of glycolysis, phosphoenolpyruvate (PEP) is converted to pyruvate and during this reaction ATP is synthesized. Based on the fact that ATP is synthesized, which of the following enzymes would most likely catalyze this reaction? a. enolase b. pyruvate kinase c. aldolase d. pyruvate isomerase e. pyruvate dehydrogenaseWhat enzyme is inhibited by the group of medications known as statins? a)HMG-CoA synthase b)Aromatase c)Fatty acid synthase d)Cyclooxygenase
- When one acetyl CoA is processed through the citric acid cycle, how many times does each of the following events occur? a. A FAD molecule is a reactant. b. A CoA-SH molecule is produced. c. A dehydrogenase enzyme is needed for the reaction to occur. d. A C5 molecule is produced.The rate limiting and committed step of the pentose phosphate pathway is catalyzed by which of the following enzymes? A. Glucose-6-phosphate dehydrogenase B. Hexokinase C. 6-Phosphogluconate dehydrogenase D. TransketolaseWhich of the following enzymes possesses a catalytic mechanism extremely similar to that of the Pyruvate Dehydrogenase Complex? A. the isocitrate dehydrogenase B. the succinate dehydrogenase C. the alpha-ketoglutarate dehydrogenase D. the malate dehydrogenase
- Which of the following citric acid cycle enzymes catalyzes substrate-level phosphorylation? A) isocitrate dehydrogenase B) α-ketoglutarate dehydrogenase C) succinyl CoA synthetase D) succinate dehydrogenase E) malate dehydrogenaseWhich of the following is NOT a component of the pyruvate dehydrogenase complex? a. dihydrolipoyl dehydrogenase b. dihydrolipoyl transacetylase c. pyruvate dehydrogenase d. dihydrolipoyl catalaseWhat enzyme will be used if only the non-oxidative portion of the pentose phosphate pathway is operating to produce ribose 5-phosphate? a) 6-phosphogluconate dehydrogenase b) 6-phosphoglucono-lactonase c) glucose 6 phosphate dehydrogenase d) transketolase
- A researcher has recently suggested that Pyruvate Dehydrogenase Complex could be source for acetate in the cell. Why would acetate production by the pyruvate dehydrogenase complex be highly unlikely to occur inside a cell.Which of the following enzyme catalyzes the conversion of pyruvate to lactate? Select one: a. Lactate reductase b. Pyruvate reductase C. Lactate dehydrogenase d. Pyruvate dehydrogenaseProvide the mechanism by which the hormone glucagon can regulate glycogen breakdown in the liver. Once this glycogen is broken down, what is the fate of the reaction product? Which metabolic pathway is it likely to proceed through next and why