a) Let's say the two motif hits (CCACGAG and CCGCCAG respectively) turn out to be evolutionarily related: What is (or are if there is more than one) the most likely ancestral sequence of these sequences in the last common ancestor? Explain what other possibilities for the ancestral sequence there might be if any. b) Based on your interpretation of the motif, which (if any) positions, 1-7, are likely required for a motif match? Construct a plausible PWM (scoring matrix) for the motif. c) If C is the only base that occurs in the first position of the motif in all identified cases of binding, explain the most likely reason why C isnt two bits high in he most bits 3 CT GSC webkage.berkeley.edu 3'

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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a) Let's say the two motif hits (CCACGAG and CCGCCAG respectively) turn out to be evolutionarily related: What is (or are if there is more
than one) the most likely ancestral sequence of these sequences in the last common ancestor? Explain what other possibilities for the
ancestral sequence there might be if any. b) Based on your interpretation of the motif, which (if any) positions, 1-7, are likely required for a
motif match? Construct a plausible PWM (scoring matrix) for the motif. c) If C is the only base that occurs in the first position of the motif in
all identified cases of binding, explain the most likely reason why C isnt two bits high in he most
bits
3
CT
GSC
weblogo.berkeley.edu
3'
Transcribed Image Text:a) Let's say the two motif hits (CCACGAG and CCGCCAG respectively) turn out to be evolutionarily related: What is (or are if there is more than one) the most likely ancestral sequence of these sequences in the last common ancestor? Explain what other possibilities for the ancestral sequence there might be if any. b) Based on your interpretation of the motif, which (if any) positions, 1-7, are likely required for a motif match? Construct a plausible PWM (scoring matrix) for the motif. c) If C is the only base that occurs in the first position of the motif in all identified cases of binding, explain the most likely reason why C isnt two bits high in he most bits 3 CT GSC weblogo.berkeley.edu 3'
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