A) Three teaspoons of water (approx. 15 ml) were added to one tablet said to contain 300 mg of aspirin. Fizzing was observed. Most of the tablet dissolved, but there were some solid particles, By heating the mug in a microwave for 10 second increments until the water came to the boil (approx. 3x), all of the solid particles dissolved. The solution was left to cool to room temperature and then placed in a fridge and NOTHING HAPPENED. Try this yourself if you can spare two aspirin tablets, your results might look different. Questions to ask: 1. What might the fizzing bubbles be? 2. Can you give a chemical explanation? 3. Can you write a chemical reaction equation with aspirin reacting with something to give a gas and aspiri in another form? 4. What might be the formulation (what the manufacturer mixes with aspirin in making the tablet) trick for aspirin to improve solubility? 5. How does this compare with the published solubility of aspirin in water?- this is a physical property of an organic compound.

A) Three teaspoons of water (approx. 15 ml) were added to one tablet said to contain 300 mg of aspirin. Fizzing was observed. Most of the tablet dissolved, but there were some solid particles, By heating the mug in a microwave for 10 second increments until the water came to the boil (approx. 3x), all of the solid particles dissolved. The solution was left to cool to room temperature and then placed in a fridge and NOTHING HAPPENED. Try this yourself if you can spare two aspirin tablets, your results might look different. Questions to ask: 1. What might the fizzing bubbles be? 2. Can you give a chemical explanation? 3. Can you write a chemical reaction equation with aspirin reacting with something to give a gas and aspiri in another form? 4. What might be the formulation (what the manufacturer mixes with aspirin in making the tablet) trick for aspirin to improve solubility? 5. How does this compare with the published solubility of aspirin in water?- this is a physical property of an organic compound.

Fundamentals Of Analytical Chemistry

9th Edition

ISBN:9781285640686

Author:Skoog

Publisher:Skoog

Chapter31: Introduction To Analytical Separations

Section: Chapter Questions

Problem 31.19QAP

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