Figure 19-18a shows a plot of P values (represented bythe dots) along the chromosomes of the dog genome.Each P value is the result of a statistical test of association between a SNP and body size. Other than the clusterof small P values near IGF1, do you see any chromosomalregions with evidence for a significant association between a SNP and body size? Explain Association mapping finds agene for body size in dogs(a)IGF1104Significance threshold10235 40 45 50 46 51 43 48 12 17 22 27 3 8chr 15chr 1chr 2chr 3 chr 34 chr 37Position (Mb)(b)FIGURE 19-18 (a) Results from anassociation-mapping experiment forbody size in dogs. Each dot in the plotrepresents the P value for a test ofassociation between a SNP and bodysize. Dots above the "threshold line"show evidence for a statisticallyGWA, genes, diOver the past 10 ye-much has been learspecies. Let's look a.genes in a group ofthe P values for assadots are the statistiesignificant association. (b) Examplesof a small and large breed of dog.[(b) (c) © Tetra images/Corbis.)chromosome 6 forP value

Alleles of genes present on different loci assort independently.

Answered: Association mapping finds a gene for…

Biology: The Unity and Diversity of Life (MindTap Course List)

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ISBN:9781305073951

Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr

Publisher:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr

Chapter33: Sensory Perception

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Problem 1CT: Like other nocturnal carnivores, the ferret shown in FIGURE 33.13 has light-reflecting material in...

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Figure 19-18a shows a plot of P values (represented by
the dots) along the chromosomes of the dog genome.
Each P value is the result of a statistical test of association between a SNP and body size. Other than the cluster
of small P values near IGF1, do you see any chromosomal
regions with evidence for a significant association between a SNP and body size? Explain

Association mapping finds a
gene for body size in dogs
(a)
IGF1
104
Significance threshold
102
35 40 45 50 46 51 43 48 12 17 22 27 3 8
chr 15
chr 1
chr 2
chr 3 chr 34 chr 37
Position (Mb)
(b)
FIGURE 19-18 (a) Results from an
association-mapping experiment for
body size in dogs. Each dot in the plot
represents the P value for a test of
association between a SNP and body
size. Dots above the "threshold line"
show evidence for a statistically
GWA, genes, di
Over the past 10 ye-
much has been lear
species. Let's look a.
genes in a group of
the P values for assa
dots are the statistie
significant association. (b) Examples
of a small and large breed of dog.
[(b) (c) © Tetra images/Corbis.)
chromosome 6 for
P value

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