At pH = 7 the wild type enzyme X has optimal activity. The H102A mutant has half the maximum activity at pH = 7? Which can be a conclusion for this data? Select all that apply: H102 acts like an acid in this reaction. H102 aids in substrate binding O H102 acts like a base in this reaction. Oa strong nucleophile is necessary for catalysis to occur.

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
icon
Related questions
icon
Concept explainers
Question
At pH = 7 the wild type enzyme X has optimal activity. The H102A mutant has half
the maximum activity at pH = 7? Which can be a conclusion for this data?
Select all that apply:
H102 acts like an acid in this reaction.
H102 aids in substrate binding
H102 acts like a base in this reaction.
a strong nucleophile is necessary for catalysis to occur.
Transcribed Image Text:At pH = 7 the wild type enzyme X has optimal activity. The H102A mutant has half the maximum activity at pH = 7? Which can be a conclusion for this data? Select all that apply: H102 acts like an acid in this reaction. H102 aids in substrate binding H102 acts like a base in this reaction. a strong nucleophile is necessary for catalysis to occur.
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Macromolecules
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON