Calculate the number of ATPs generated from the metabolic oxidation of the four carbons of acetoacetyl-CoA to CO2. Now consider the homolog derived from oxidation of an odd-numbered carbon chain, namely, propionoacetyl-CoA. Calculate the net ATP yield from oxidation of the five carbons of this compound to CO2.

Calculate the number of ATPs generated from the metabolic oxidation of the four carbons of acetoacetyl-CoA to CO2. Now consider the homolog derived from oxidation of an odd-numbered carbon chain, namely, propionoacetyl-CoA. Calculate the net ATP yield from oxidation of the five carbons of this compound to CO2.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter19: The Tricarboxylic Acid Cycle

Section: Chapter Questions

Problem 21P: Complete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and...

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Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is inhibited byÂ· NIADH. Pyruvate dehydrogenase is inhibited by AÎ¤Î¡. Citrate synthase is inhibited by NADH. Succinyl-CoA activates citrate synthase. Acetyl-CoA activates pyruvate carboxylase.
Compare the energy cost, in ATP equivalents, of synthesizing stearate from mitochondrial acetyl-CoA to the energy recovered by degrading stearate to acetyl-CoA.
Calculate the number of ATPs generated from the metabolic oxidation of the four carbons of acetoacetyl-CoA to CO2. Now consider the homolog derived from oxidation of an odd-numbered carbon chain, namely, propionoacetyl- CoA. Calculate the net ATP yield from oxidation of the five carbons of this compound to CO2.
If oxidation of acetyl-CoA yields 10 ATPs per mole through the citric acidcycle, how many ATPs will be derived from the complete metabolic oxidation of 1 mole of alanine in a mammal? Would the corresponding energyyield in a fish be higher or lower? Why? How much energy would bederived from the metabolic oxidation of 1 mole of isoleucine to CO2, H2O,and NH3? Of tyrosine?
How many ATP can be produced by the complete oxidation of each propionyl-CoA product of fatty acid oxidation? Compare this to the ATP yield for each acetyl-CoA.
Fourteen NADPH molecules are required to produce one molecules of palmitic acid from acetyl CoA. Substantiate this statement by referring to the enzymatic activities involved in reduction steps during fatty acid synthesis and the number of cycles required to produce palmitic acid from acetyl CoA. How many molecules of ATP is required for the synthesis of palmitic acid from cytosolic acetyl-CoA?
If oxidation of acetyl-CoA yields 10 ATPs per mole through the citric acid cycle, how many ATPs will be derived from the complete metabolic oxidation of 1 mole of alanine in a mammal? Would the corresponding energy yield in a fish be higher or lower? Why? How much energy would be derived from the metabolic oxidation of 1 mole of isoleucine to CO2, H2O, and NH3? Of tyrosine?
The CO2 produced in one round of the citric acid cycle does not originate in the acetyl carbons that entered that round. (a) How many rounds are required before 14CO2 is released if acetyl-CoA is labeled at its methyl group? (b) If acetyl-CoA is labeled with 14C at its carbonyl carbon, how many rounds of the cycle are required before 14CO2 is released?
In the first step of the TCA cycle the acetyl group of acetyl-CoA is transferred to oxaloacetate to produce citrate. Where will the carbonyl carbon of that acetyl group be after the first CO2 is expelled? Group of answer choices The first carbon of α-ketoglutarate The last carbon of α-ketoglutarate The fourth carbon of α-ketoglutarate The third carbon of α-ketoglutarate
If the carbonyl carbon of acetyl-CoA were marked with 14C, where would that carbon be located within oxaloacetate after one turn of the TCA cycle?
The CO2 produced in one round of the citric acid cycle does not originate in the acetyl carbons that entered that round. If acetyl-CoA is labeled with 14C at its carbonyl carbon, how many rounds of the cycle are required before 14CO2 is released?
Consider the complete oxidation of one mole of the fatty acyl CoA of capric acid (10:0). Determine the following: rounds of β-oxidation total no. of acetyl CoA produced total no. of NADH produced from all rounds of β-oxidation total no. of FADH2 produced from all rounds of β-oxidation total no. of NADH produced from the oxidation of all acetyl CoA in the TCA cycle total no. of FADH2 produced from the oxidation of all acetyl CoA in the TCA cycle total ATP yield