. Certain microorganisms with a modified citric acid cycle decarboxylate a-ketoglutarate to produce succinate semialdehyde: COO-Coo-co,CH,CH,CH,CH,C=0c=0Ha-KetoglutarateSuccinate semialdehyde(a) Succinate semialdehyde is then converted to succinate, which is furthermetabolized by standard citric acid cycle enzymes. What kind of reactionis required to convert succinate semialdehyde to succinate? Show anycoenzymes that might be involved.(b) Based on your answer in part a, how does this pathway compare to thestandard citric acid cycle in energy yield?

Succinate semialdehyde is an intermediate formed during the bacterial citric acid cycle it is also…

Answered: . Certain microorganisms with a…

Chemistry for Today: General, Organic, and Biochemistry

9th Edition

ISBN:9781305960060

Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen

Publisher:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen

Chapter23: Carbohydrate Metabolism

Section: Chapter Questions

Problem 23.80E

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Similar questions

The reaction for “activation” of a fatty acid (RCOO−), ATP + CoA + RCOO−⇌ RCOOCoA + AMP + PPi has ΔG°′ = +4.6 kJ · mol−1. What is the thermo dynamic driving force for this reaction?
Which of the reactions are spontaneous (favorable)? 1)DHAP↽−−⇀glyceraldehyde-3-phosphateΔ?=3.8 kJ/mol 2)L-malate+NAD+⟶oxaloacetate+NADH+H+Δ?=29.7 kJ/mol- 3) glutamate+NAD++H2O⟶NH+4+α-ketoglutarate+NADH+H+Δ?=3.7 kcal/ 4) C6H13O9P+ATP⟶C6H14O12P2+ADPΔ?=−14.2KJ/mol 5) −Rh(I)C2H6Δ?=−150.97 kJ/molC2H4+H2→Rh(I)C2H6ΔG=−150.97 kJ/mol 6) C4H4O5⟶C4H2O4+H2OΔ?=3.1 kJ/mol
12. Protein catabolism can yield which of the following: 1. Complex carbohydrates 2. Glucose 3. Free fatty acids 4. Omega-3 fatty acids
Why is the reaction that is catalyzed by E3 in the oxidative decarboxylation of pyruvate by the pyruvate dehydrogenase complex not involved in the forming of the product (acetyl CoA) but still is important to the process of the complex? Explain why it is important.
If the hydrolysis of 1 M glucose 6-phosphate catalyzed by glucose 6-phosphatase has a delta G’^o of -11.386 kJ/mol at 25 °C, what percentage of substrate remains once the reaction reaches equilibrium assuming no product was initially present? (Round answer to the nearest whole number) (R = 8.315 J/mol · K)
Which intermediate(s) in the citric acid cycle contain two chirality centers? Which intermediate(s) contain a secondary alcohol? Please write the name(s) of the intermediate(s) given beneath the structures.
Find out the role and chemical reactions of the following reagents in the blood glucose level determination by glucose oxidase method. a) Sodium sulphate – Zinc sulphate solution b ) Glucose oxidase reagent c) Peroxidase
The vitamin Niacin is used to form nicotinamide adenosine dinucleotide, which readily shuttles between its oxidized (NAD+) and reduced (NADH) forms. The latter serves as a cellular equivalent to NaBH4. The essential portions of the structures are shown below. Outline a mechanism for the cellular conversion of pyruvate to lactate. (Note: like NaBH4, NADH cannot reduce carboxylic acid carbonyls).
Triose phosphate isomerase catalyzes the conversion of dihydroxyacetone phosphate (DHAP) into glyceraldehyde-3-phosphate (G3P). Which of the following illustrates this chemical reaction? a) A b) B c) C d) D
The oxidation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate is an endergonic reaction, but the flow through this point in glycolysis proceeds smoothly. How is the unfavorable equilibrium constant overcome?
Anaerobic glycolysis (i.e., lactic acid fermentation) produces pyruvate that is then converted to lactate through the activity of lactate dehydrogenase. The conversion of pyruvate to lactate would seem to be an unnecessary step, since this process does not result in any further release of energy. Explain the necessity for the production of lactate as the endpoint for anaerobic glycolysis.
The rate-limiting step is a metabolic pathway is the slowest step which determines the overall rate of the other reactions in the pathway. In glycolysis, the rate limiting step is a phosphorylation reaction where phosphofructokinase (PFK-1) catalyzes the reaction fructose-6-bisphosphate -> fructose-1,6-bisphosphate, the same step in gluconeogenesis. Select one: The statement is FALSE. The statement is TRUE.

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