Compare the regulation of the pyruvate dehydrogenase complex in muscle and in liver.

Q: 182. Pyruvate dehydrogenase is inhibited allosterically by- a) AMP c) NADH b) Pyruvate d) Insulin…

A: Pyruvate dehydrogenase is regulated by :-  1) Allosteric regulation - components of PDH complex -…

Q: Identify the means by which the pyruvate dehydrogenase complex is regulated.

A: Pyruvate dehydrogenase is a convergence point in the regulation of the metabolic finetuning between…

Q: Briefly describe the dual role of lipoic acid in the pyruvate dehydrogenase complex

A: Lipoic acid is essentially used in aerobic processes. It is important biological compound for the…

Q: Describe the fate of glycerol generated from triacylglycerolhydrolysis in adipocytes.

A: When triacylglycerols is mobilized from the fat tissue, its hydrolysis to free fatty acids and…

Q: Explain what will happen to reactions of pyruvate dehydrogenase complex when there is a deficiency…

A: Pyruvate dehydrogenase complex (PDC) is a complex formed by 3 enzymes that converts pyruvate into…

Q: Explain the efficiency of using the citric acid cycle to oxidize acetyl CoA.

A: The citric acid cycle or TCA cycle is a series of chemical reactions used by all aerobic organisms…

Q: Draw a plausible mechanism for the oxidative decarboxylation of isocitrate by isocitrate…

A: Isocitrate dehydrogenase is an enzyme that catalyzes the oxidative decarboxylation of isocitrate,…

Q: a) describe the overall reaction catalyzed by the pyruvate dehydrogenase complex (PDH) and its…

A: 1) a) Pyruvate dehydrogenase complex comprises three enzymes- Pyruvate dehydrogenase (E1),…

Q: Give one metabolic intermediate that is released as pyruvate is oxidized by the pyruvate…

A: Glucose is metabolized through the glycolytic pathway to synthesize energy in the form of ATP and…

Q: Explain the Allosteric regulation of glucose metabolism.

A: Glycolysis involves the breakdown of glucose to pyruvate to synthesize ATP. Glycolysis is divided…

Q: Explain why inhibiting the activity of acetyl-CoA carboxylase might not affect a person’s body mass.

A: Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme that catalyzes the irreversible…

Q: Describe the reaction catalyzed by each enzyme: (a) aspartate transaminase; (b) glyceraldehyde…

A: Introduction: a) Transamination is the transfer of an amino group from one amino acid to an α-keto…

Q: write a balanced equation for the overall reaction catalyzed by each of the three enzymes in the…

A: The pyruvate dehyrdrogenase complex is complex of 3 enzymes that plays a role in the metabolsim by…

Q: Describe the mechanism in which NADH is involved in the activation of oxygen molecules in fatty acid…

A: The desaturation of fatty acids is done by an enzyme called fatty acyl-CoA desaturase. It removes…

Q: NADH can act as an inhibitor of isocitrate dehydrogenase and a-ketoglutarate dehydrogenase. This is…

A: Hi! As you have posted multiple questions  which is to be answered, we are authored to answer  first…

Q: Briefly discuss the process of glycogen catabolism in atep by step

A: Glycogenolysis is the catabolic process of glycogen and this is involved in the release of energy.…

Q: Explain the function of glucagon and the reaction that is being catalyzed in glycogenolysis

A: Hormones are chemical messengers that are produced by endocrine glands of the body and are…

Q: L In which steps of the aerobic processing of pyruvate isCO2 produced?

A: Glucose is the primary energy source in living organisms. Glucose is broken down to form two…

Q: Briefly describe the fate of pyruvate in metabolism under anaerobic versus aerobic conditions

A: Aerobic glycolysis occurs in presence of oxygen where oxidation of glucose takes place and converted…

Q: Describe the advantage of regenerating oxaloacetate at the end of each turn of the citric acid…

A: ATP is the energy currency for all living cells. The citric acid cycle is also known as the…

Q: Identify the primary catabolic purpose of the citric acid cycle

A: The citric acid (CAC) cycle is the primary catabolic process, which helps to convert the pyruvate…

Q: Describe two different ways in which glucose oxidase is regulated.

A: Answer: - Glucose oxidase is a subset of oxidoreductase compounds that catalyzes the exchange of…

Q: Distinguish between catalytic coenzymes and stoichiometric coenzymes in the pyruvate dehydrogenase…

A: The Pyruvate dehydrogenase complex consists of five different coenzymes such as thiamine…

Q: Explain How arsenic affects the pyruvate dehydrogenase reaction

A: Pyruvate dehydrogenase reaction is a reaction in which pyruvate is converted into acetyl-CoA.

Q: What is the physiologic significance of pyruvate dehydrogenase complex?What's the biochemical basis…

A: Hi! As you have asked multiple questions, we are answering only the first two for you. If you need…

Q: Outline the conditions that direct pyruvate toward the following:(a) Entry into the citric acid…

A: Since you have posted a question with multiple sub-parts, we will solve first three sub-parts for…

Q: Describe the fate of pyruvate under anaerobic and aerobicconditions.

A: Anaerobic : It occurs when the uptake or disappearance of oxygen is greater than its production by…

Q: Correlate the importance of Citric Acid Cycle in maintaining the glucose hemeostasis.

A: The citric acid cycle involves the oxidation of acetyl CoA into CO2 and H2O. It is the final common…

Q: Explain why the first step of glucose catabolism is necessary.

A: The catabolism of Glucose, i.e., Glycolysis, is very important for the cell as glucose is the main…

Q: In the Cori cycle, the lactate product of glycolysis in muscle is transformedback into glucose by…

A: Cori cycle is a metabolic pathway in which lactate is converted in glucose by the process of…

Q: Explain the reasons for the oxidation of acetate through complex pathways in the citrate cycle.

A: TCA or tricarboxylic acid cycle is the second step of aerobic cellular respiration. It is an…

Q: Describe the sources and fates of acetyl CoA

A: The enzyme which takes part in the various biochemical reaction and delivering of the acetyl group…

Q: describe how the pyruvate dehydrogenase complex is regulated?

A: Pyruvate dehydrogenase complex (PDC) is a three-enzyme complex that decarboxylates pyruvate into…

Q: Calculate the net number of ATPs produced when one 10-carbon fatty acid is activated, enters the…

A: Fatty acids are the building blocks of fat in both our body and our meals. The body breaks down…

Q: Draw a plausible mechanism for the oxidation of dihydrolipoamide to lipoamide by the E, subunit…

A: A trivial term for 6,8-dithiooctanoic amide is lipoamide. Lipoamide is an efficient form of lipoic…

Q: The TCA cycle entails eight enzymatically catalyzed steps starting with the entry of acetyl-CoA into…

A: The Tricarboxylic acid cycle (Citric acid cycle) is the main energy-producing metabolic pathway in…

Q: L What is the difference between the type of oxidation catalyzed by acyl-CoA dehydrogenase and that…

A: Fatty Acid Oxidation is a major source of energy for the body in tissues that require more energy…

Q: Describe the role played by each enzyme, cofactor, andcoenzyme of the pyruvate dehydrogenase complex

A: Introduction: The conversion of pyruvate to acetyl-CoA is done by oxidative decarboxylation. This…

Q: Predict which one of the five steps of the a-ketoglutarate dehydrogenase complex reaction is…

A: α ketoglutarate dehydrogenase complex is an enzyme complex that catalyzes the conversion of α…

Q: Discuss how the isozymic forms of acetyl CoA carboxylase regulate fatty acid metabolism. Explain the…

A: The single controlled enzyme in fatty acid synthesis is acetyl-CoA carboxylase, which catalyzes the…

Metabolic pathways

Metabolism is defined as the group of life-supporting, enzyme-mediated chemical reactions in organisms. A metabolic pathway is a set of these chemical reactions that involve anabolism (synthesis of complex biomolecules) and catabolism (breakdown of biomolecules into small molecules) that occur inside a cell. Metabolites are the reacting substances, products, and intermediate substances of an enzymatic process that are altered by a series of chemical events catalyzed by enzymes.