Define the silent mutation in DNA? (2.5 marks) 2) What is the codon usage bias? (2.5 marks) 3) Provide one example of a clinical implication of a “silent mutation” that proven to have an effect on the phenotype and provide a brief description of its molecular characteristics? (10.0 marks)

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Silent mutations that occur in DNA are quite common in living cells and usually involve no effects on
phenotype. In not more than 2 pages (using 1.5 line space of Arial or Times New Roman fonts) provide
answers for the following questions?
1) Define the silent mutation in DNA? (2.5 marks)
2) What is the codon usage bias? (2.5 marks)
3) Provide one example of a clinical implication of a “silent mutation” that proven to have an effect on
the phenotype and provide a brief description of its molecular characteristics? (10.0 marks)

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