Discuss the difference between first-generation and second-generation antihistamines
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Discuss the difference between first-generation and second-generation antihistamines.
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- Why is the use of first-generation H1-antihistamines discouraged in clinical practice today?Describe the major characteristics and actions of antihistamines. What is a difference between first and second generation of antihistamines?.) How can these physiological factors listed below affect drug effect? Explain each. - diurnal rhythm - acid - base balance - hydration - electrolyte balance।
- What are the potential implications of genetic variations in drug-metabolizing enzymes on individual response and therapeutic outcomes in clinical pharmacology?How we can improve pharmacokinetic parameters for the development of H1-Antihistamine ? DiscussDescribe the mechanism of action of antiretrovirals?