Duchenne muscular dystrophy is caused by a mutation in a gene that comprises 2.5 million base pairs and specifies a protein called dystrophin. However, less than 1% of the gene actually encodes the amino acids in the dystrophin protein. On the basis of what you now know about gene structure and RNA processing in eukaryotic cells, provide a possible explanation for the large size of the dystrophin gene.

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
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Chapter11: Genome Alterations: Mutation And Epigenetics
Section: Chapter Questions
Problem 10QP: If the coding region of a gene (the exons) contains 2,100 base pairs of DNA, would a missense...
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Duchenne muscular dystrophy is caused by a mutation in a gene that
comprises 2.5 million base pairs and specifies a protein called
dystrophin. However, less than 1% of the gene actually encodes the
amino acids in the dystrophin protein. On the basis of what you now
know about gene structure and RNA processing in eukaryotic cells,
provide a possible explanation for the large size of the dystrophin gene.

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