E23. In the Western blot shown here, proteins were isolated from red blood cells and muscle cells from two different individuals. One individual was unaffected, and the other suffered from a disease known as thalassemia, which involves a defect in hemoglobin. The blot was exposed to an antibody that recognizes B globin, which is one of the polypeptides that constitute hemoglobin. Equal amounts of total cellular proteins were added to each lane. Lane 1: Proteins isolated from normal 2 3 4 red blood cells Lane 2: Proteins isolated from the red blood cells of a thalassemia patient Lane 3: Proteins isolated from normal muscle cells Lane 4: Proteins isolated from the muscle cells of a thalassemia patient Explain these results.

Human Heredity: Principles and Issues (MindTap Course List)
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E23. In the Western blot shown here, proteins were isolated from red
blood cells and muscle cells from two different individuals. One
individual was unaffected, and the other suffered from a disease
known as thalassemia, which involves a defect in hemoglobin. The
blot was exposed to an antibody that recognizes B globin, which is
one of the polypeptides that constitute hemoglobin. Equal amounts
of total cellular proteins were added to each lane.
Lane 1: Proteins isolated from normal
2
3
4
red blood cells
Lane 2: Proteins isolated from the red
blood cells of a thalassemia
patient
Lane 3: Proteins isolated from normal
muscle cells
Lane 4: Proteins isolated from the
muscle cells of a thalassemia
patient
Explain these results.
Transcribed Image Text:E23. In the Western blot shown here, proteins were isolated from red blood cells and muscle cells from two different individuals. One individual was unaffected, and the other suffered from a disease known as thalassemia, which involves a defect in hemoglobin. The blot was exposed to an antibody that recognizes B globin, which is one of the polypeptides that constitute hemoglobin. Equal amounts of total cellular proteins were added to each lane. Lane 1: Proteins isolated from normal 2 3 4 red blood cells Lane 2: Proteins isolated from the red blood cells of a thalassemia patient Lane 3: Proteins isolated from normal muscle cells Lane 4: Proteins isolated from the muscle cells of a thalassemia patient Explain these results.
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