Fill up the blank  __________s are blood diseases caused by mutationsthat eliminate or reduce the production of globinpolypeptides from one of the clusters but not the other.These mutations can include deletions of specific genesor the LCR in either cluster.

Q: What results can happen when ultraviolet radiation is used (i.e. thymine dimers) and this will…

A: When adjacent thymidine residues are covalently connected in presence of ultraviolet radiation,…

Q: Ehler-Danlos syndrome is a rare disorder caused by a mutation ina gene that encodes a protein called…

A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…

Q: Six months pregnant, an expectant mother had a routineultrasound that showed that the limbs of the…

A: Achondroplasia is an abnormality related to bone growth that includes obstruction in the formation…

Q: In an epic battle, the Green Goblin was able to wound Spider-Man aind collect a samplle of his…

A: Crossing over is a phenomenon that occurs in the linked genes. When the crossing over occurs between…

Q: Loss of function mutation results in a _ allele.

A: Mutations are sudden changes in the gene sequence. When these changes causes loss of function of an…

Q: Hemophilia results from a sex-linked gene. The disease is most common in males, but the hemophilia…

A:

Q: Spherocytosis is an inherited blood disease in whichthe erythrocytes (red blood cells) are spherical…

A: Penetrance is defined as the proportion of individuals who carries a specific variant or mutated…

Q: While examining a human female, you discover that she has 44 autosomes and two sex chromosomes, an X…

A: Chromosomes are DNA molecules that possess the genetic material in them. Chromosomes are present in…

Q: Thomas discovered a devastating piece of family historywhen he learned that his brother had been…

A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…

Q: hair, underdeveloped nails, and abnormally shaped eyelids. In the following pedigree, which…

A:

Q: A particular disease is found in a group of South AmericanIndians. During the 1920s, many of these…

A: Any abnormal condition which affects the functions or structure of either the whole body or some…

Q: A loss of function mutation in both alleles of the Bcl2 gene A loss-of-function mutation in both…

A: For the cell to evade apoptotic pathways, they need to get rid of things which kill the cell as is…

Q: Phenylketonuria (PKU) is a disorder caused by a defect in the gene that codes for the phenylalanine…

A: Introduction  Phenylketonuria is a metabolic disorder which has inheritance pattern of autosomal…

Q: In mice, the autosomal locus coding for the β-globinchain of hemoglobin is 1 m.u. from the albino…

A: Since you have posted a question with multiple sub-parts, we are answering only first one for you.To…

Q: In certain animals, such as alligators, sex is determined by temperature.When alligator eggs are…

A: Alligators are reptiles, some undergo parthenogenesis, and alligators' sex is determined by…

Q: Phenylketonuria (PKU) is a disorder caused by a defect in the gene that codes for the phenylalanine…

A: Introduction  Pedigree Analysis: this is the new approach to study the inheritance pattern in the…

Q: A cystic-fibrosis mutation in a certain pedigree is due toa single nucleotide-pair change. This…

A: To explain: To explain about careers of cystic fibrosis and the risks of having cystic fibrosis…

Q: A man in his early 30s suddenly developed weakness in hishands and neck, followed weeks later by…

A: Based on the age of onset and the severity of the symptoms, the DM1 (myotonic dystrophy type 1)…

Q: This lysosomal storage disease is inherited in an X linked manner from a mother who often presents…

A: Lysosomal storage illnesses are inherited metabolic diseases defined by an abnormal accumulation of…

Q: In humans, hemophilia is an X-linked recessive gene and will only be expressed in females if they…

A: Hemophilia is an inherited disorder where blood doesn't clot properly due to loss of body's capacity…

Q: . Usually, the deletion of a gene results in a recessive mutation. Explain how the deletion of an…

A: A recessive mutation is one in which the mutated gene has to be present on both of the homologous…

Q: In retinoblastoma, a mutation in one allele of the RB1 tumorsuppressorgene can be inherited from the…

A: Retinoblastoma is a rare retinal disease that develops a malignant tumor in the retinal layers of…

Q: The pedigree here shows the inheritance of a human disease knownas familial hypercholesterolemia.…

A: Pedigree analysis can be described as the record of a special genetical character or a disorder for…

Q: Six months pregnant, an expectant mother had a routineultrasound that showed that the limbs of the…

A: In genetics, achondroplasia is defined as the rare type of genetic disorder related to the growth of…

Q: Traits are inherited germ line wise (vertical inheritance) and somatic (epigenetics) inheritance,…

A: Inheritance or heredity refers to the transfer of traits or characters from parents to subsequent…

Q: Sickle cell anemia is an autosomal recessive genetic disorder. Because individuals affected by…

A: As malaria becomes less deadly, selection for a genetic mutation that protects individuals from the…

Q: If scientists are successful in reducing significantly or eliminating malaria, the best prediction…

A: Sickle cell anemia refers to the most common type of sickle cell disorder which is characterized by…

Q: Phenylketonuria (PKU) is a disorder caused by a defect in the gene that codes for the phenylalanine…

A: Phenyl ketonuria is a autosomal recessive disorders. The baby is affected it means he is homozygous…

Q: A mutation on an autosome causes a particular protein to be overproduced, and the excess protein…

A: Mutations are random changes in the genome.

Q: An nonsense mutation in the gene for a human enzyme is most likely to be Dominant Recessive…

A: Nonsense mutations  The change is single nucleotide base which leads to the production of defective…

Q: A man in his early 30s suddenly developed weakness in hishands and neck, followed weeks later by…

A: Myotonic dystrophy (DM) is the second most frequent type of muscular dystrophy. In the most severe…

Q: Bloom syndrome is an autosomal recessive disease that exhibitshaploinsufficiency. A recent survey…

A: A disease is a state of unhealthiness of the physical body, mind and social interaction. A disease…

Q: CdLS is usually caused by new mutation in oneparent’s gamete. Why?

A: The changes in the sequence of nucleotides are called mutations. The agents that cause mutations are…

Q: >chromosomal…

A: Codons are trinucleotide sequence that codes for specific amino acids and there are totals of 64…

Q: Explain the following diagram. It refers to a pedigree on the disease called phenylketonuria.…

A: Phenylketonuria is an inherited disorder that increases the levels of a substance called…

Q: myoglobin and alpha globin in humans O orthologous genes O paralogous genes pseudogenes O all of…

A: a. Homology means similarity between the characters as it is shared from the ancestry and its forms…

Q: The following chromosomal aberration is found in nearly 90-95% of all patients who have chronic…

A: In chronic myelogenous leukemia, BCR and ABL genes in close proximity on chromosome -22 BCR (present…

Q: Duchenne muscular dystrophy (DMD) is caused bya recessive mutant allele of an X-linked gene…

A: Duchenne muscular dystrophy (DMD) is a progressive form of muscular dystrophy that results in muscle…

Q: Comparing the colchicine-treated cell and the untreated cell, what general type of chromosomal…

A: Colchicine is a microtubule destabilizing drug and is used for the treatment of rheumatoid…

Q: A man in his early 30s suddenly developed weakness in hishands and neck, followed weeks later by…

A: Introduction  A genome is consisting of transcriptionally active genes. These genes form mRNA as…

Q: Albinism occurs when cells cannot chemically synthesize pigment molecules. This occurs because the…

A: Albinism is a category of genetic illnesses in which the pigment melanin, which affects the colour…

Q: A human gene called the β-globin gene encodes a polypeptidethat functions as a subunit of the…

A: AS per our honor code, we are allowed to answer only one question with a maximum of three-subparts.…

Q: Galton’s traits are readily observed in everyday life. What did Galton discover?

A: Mendel proposed the laws of inheritance based on his results of the hybridization experiments

Q: The accompanying pedigree shows a very unusual inheritance pattern that actually did exist. All…

A: Part A. There is the probability of carrying a lethal gene by the X chromosome which is inactivated.…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.