H2B НЗ Histone octamer нз 11 nm DNA H2A НА Linker region Н2В Н2А Globular domain One histone protein Amino terminal Nucleosome- tail 8 histone proteins + 146 or 147 base pairs of DNA (a) Nucleosomes showing core histone proteins сoге (b) Molecular model for nucleosome structure Histone octamer Nonhistone proteins Linker FIGURE 10.10 Nucleosome structure. (a) A nucleosome con- histone (H1) sists of 146 or 147 bp of DNA wrapped around an octamer of core histone proteins. (b) A model for the structure of a nucleosome as determined by X-ray crystallography. The drawing shows two views of a nucleosome Linker that are at right angles to each other. (c) The linker region of DNA connects adjacent nucleosomes. The linker histone H1 and nonhistone proteins also bind to this linker region. DNA (b): © Laguna Design/SPL/Science Source (C) Nucleosomes showing linker histones and nonhistone proteins CONCEPT CHECK: What is the diameter of a nucleosome?
DNA and RNA
Deoxyribonucleic acid (DNA) is usually called the blueprint of life. Deoxyribose is a monosaccharide that has a key function in the synthesis of deoxyribonucleic acid. One less oxygen-containing hydroxyl group occurs in deoxyribose sugar. Nucleic acid, deoxyribonucleic acid, is one of the natural components. Deoxyribonucleic acid is a double-stranded molecule. Watson and Crick postulated the double-stranded model of the helix. A deoxyribonucleic acid is a molecular group that carries and transmits genetic information from parents to offspring. All eukaryotic and prokaryotic cells are involved.
DNA as the Genetic Material
DNA, or deoxyribonucleic acid, is a long polymeric nucleic acid molecule discovered in the late 1930s. It is a polymer; a long chain-like molecule made up of several monomers connected in a sequence. It possesses certain characteristics that qualify it as a genetic component. Certain organisms have different types of nucleic acids as their genetic material - DNA or RNA.
Genetics
The significant branch in science which involves the study of genes, gene variations, and the organism's heredity is known as genetics. It is also used to study the involvement of a gene or set of genes in the health of an individual and how it prevents several diseases in a human being. Thus, genetics also creates an understanding of various medical conditions.
DNA Replication
The mechanism by which deoxyribonucleic acid (DNA) is capable of producing an exact copy of its own is defined as DNA replication. The DNA molecules utilize a semiconservative method for replication.
What is the diameter of a nucleosome?
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