H2N OH Br (CH;CH)N quinapril racemic A B

Q: Draw the expected product: Cl2 H2O

A: The given reaction is,

Q: Which molecule is hydrolyzed most slowly with aqueous NAOH? D. C. В. A.

A:

Q: When 2-methylcyclohexanone is treated with pyrrolidine, two isomeric enamines areformed.Why is…

A: Given: When 2-methylcyclohexanone is treated with pyrrolidine, two isomeric enamines are formed as…

Q: What reagents are needed to convert each compound to acetophenone (C6H5COCH3)?

A: Reagent use to convert acetophenone (C6H5COCH3) to Benzene (C6H6) is CH3COCl in presence of AlCl3.

Q: Draw a stepwise mechanism for the following reaction, one step in the synthesis of the…

A: A stepwise mechanism for the following reaction, one step in the synthesis of the…

Q: Hydroxy aldehydes A and B readily cyclize to form hemiacetals. Draw the stereoisomers formed in this…

A: Hemiacetal is a compound which is generated by the addition of alcohol to the aldehyde. Another…

Q: Draw a stepwise mechanism for the following reaction, one step in the synthesis of the…

A: The stepwise mechanism for the following reaction is given as- Here Grignard reagent (CH3CH2MgBr)…

Q: Draw the product formed when pentanal (CH3CH2CH2CH2CHO) is treatedwith following reagent. With some…

A: The product of the chemical reaction when pentanal (CH3CH2CH2CH2CHO) is treated with HC≡CNa and H2O…

Q: (a) Explain how NaBH4 in CH3OH can reduce hemiacetal A to butane-1,4-diol (HOCH2CH2CH2CH2OH). (b)…

A: The reaction of hemiacetal A will be given by the sodium borohydride in presence of methanol as-

Q: Draw the product formed when each starting material is treated with LDA in THF solution at −78 °C.

A:

Q: Although codeine occurs in low concentration in the opium poppy, most of the codeine used in…

A:

Q: (a) Explain how NaBH4 in CH3OH can reduce hemiacetal A to butane-1,4-diol (HOCH2CH2CH2CH2OH). (b)…

A: (a) The given compound A is a hemiacetal. Sodium borohydride (NaBH4) is a strong reducing agent. It…

Q: Quinapril (trade name Accupril) is used to treat high blood pressure and congestive heart failure.…

A:

Q: One step in the synthesis of the antihistamine fexofenadine involves acid-catalyzed hydration of the…

A: Acid catalyzed hydration of alkynes- Acid catalyzed hydration of alkynes produce ketone.…

Q: Aspartame, the sweetener used in the commercial products NutraSweet and Equal, is 200 times sweeter…

A: Aspartame is the sweetener that is used in NutraSweet and Equal and it is 200 times more sweetener…

Q: When 2-heptine was treated with aqueous sulfuric acid containing mercury(II) sulfate, two products…

A: When 2-heptyne was treated with aq. H2SO4 containing mercury (II) sulphate  There are two products…

Q: What is the major enolate (or carbanion) formed when each compound istreated with LDA?

A:

Q: Compound A is a derivative of the carbohydrate perosamine, which is found in the antibiotic…

A: Introduction: Antibiotics are drugs that help the body to fight bacterial functions. Antibiotics…

Q: One synthesis of the cholesterol-lowering drug atorvastatin involves the construction of the pyrrole…

A: The organic conversions take place in more than one step with the help of various reagents.

Q: 7.70 Quinapril (trade name Accupril) is used to treat high blood pressure and congestive heart…

A: Diastereomers are non mirror image and non identical stereoisomers

Q: Attenol A and pinnatoxin A are natural products isolated from marine sources. (a) Locate the…

A: The diether derivates of the aldehydes and ketones are known as acetals or ketals. The imine is a…

Q: Identify the lettered compounds in each reaction sequence.Draw the product formed when…

A: Grignard reagent acts as a nucleophile whereas the C of CO is an electrophilic centre.

Q: When 2-methyleyclohexanone is treated with pyrrolidine, two isomeric enamines are formed. H* + H20 A…

A:

Q: Draw the products formed (including stereoisomers) when each compound is reduced with NaBH4 in…

A: (a) The given compound is,

Q: Draw the product formed when phenylacetonitrile (C6H5CH2CN) is treated with each reagent. a. H3O+ b.…

A: “Since you have posted a question with multiple sub-parts, we will solve first three sub-parts for…

Q: What is the major enolate (or carbanion) formed when each compound is treated with LDA?

A: The major product of enolate (carbanion) formed when the compound is treated with LDA is given…

Q: What results when dimethylsulfide is treated with methyl iodide? 1) CH,I 2)- NH 3) -H A. B. C. D.

A: The reaction taking place is given as,

Q: (R)-Carvone, the major component of the oil of spearmint, undergoes acid-catalyzed isomerization to…

A: Acid-catalyzed isomerization of R carvone leads to the product carvacrol which is more stable than…

Q: Which of the following reagents are the most suitable to distinguish between ethanal CH.CHO and…

A: Ethanal (CH3CHO) and propanal (CH3CH2CHO) both are aldehyde. Ethanal has keto methyl group but…

Q: What product is formed when each compound undergoes anintramolecular reaction in the presence of…

A: The formation of a cyclic hemiacetal is an acid catalyzed reaction. The cyclic hemiacetals formed by…

Q: An allylic alcohol contains an OH group on a carbon atom adjacent to a C − C double bond. Treatment…

A: Since the reaction of alcohol with HCl can go through both SN1 and SN2 reactions. Hence when it…

Q: Treatment of ethyl acetoacetate with NaOEt (2 equiv) and BrCH2CH2Br forms compound X. This reaction…

A: The structure of "X" in the formation of illudin-S by acetoacetic ester synthesis is shown below.

Q: 1. Draw the structure of the organic product/s when: 1. propanal reacts with ammoniacal AgNO,…

A:

Q: Aspirin is an anti-inammatory agent because it inhibits the conversion of arachidonic acid to…

A:

Q: Draw a stepwise mechanism for the following reaction, the last step in a five-step industrial…

A: The stepwise mechanism is as follows:

Q: Draw the product formed when each starting material is treated with LDA in THF solution at −78 °C.

A: The product formed when the given starting material is treated with LDA in THF solution at -78°C has…

Q: What product is formed when 2-acetylcyclopentanone is treated withNaOCH2CH3, followed by CH3I?

A: The product formed on treatment of 2-acetylcyclopentanone with NaOCH2CH3 followed by CH3I is drawn…

Q: Vhen the halohydrin is treated with NaH, a product of molecular formula C¸H§O is formed. Draw the…

A: When halohydrin is treated with NaH, epoxide is formed.

Q: (R)-Carvone, the major component of the oil of spearmint, undergoes acid-catalyzed isomerization to…

A: The protonation of (R)- carvone is show below.

Q: Quinapril (trade name Accupril) is used to treat high blood pressure and congestive heart failure.…

A: Quinapril drugs is used to inhibit the action of ACE (Angiotensin Converting Enzyme) in the body. It…

Q: What product is obtained from the reaction of N,N-dimethylaniline with nitrous acid? A.…

A: The product obtained from the reaction of N,N-dimethylaniline with nitrous acid is given below.

Q: An acid–base reaction of (R)-sec-butylamine with a racemic mixture of 2phenylpropanoic acid forms…

A: Racemic mixture of 2-phenylpropanoic acid consists of R and S forms (enantiomers). Both these forms…

Q: A key step in the synthesis of the narcotic analgesic meperidine (trade name Demerol) is the…

A: a) Please see the attached picture. b) Acidic Ethanolysis Please see: Analgesics by R.S. Vardanyan,…

Q: How many stereogenic centers are present in the following tetraalkylammonium salt? Draw all possible…

A: In the given compound nitrogen atom and one carbon atom is bonded to four different groups. The…

Q: a) What two products are obtained when acetic anhydride reacts with N-isopropyl butanamine? Be sure…

A:

Q: Draw a stepwise mechanism for the following reaction, the last step in a five-step industrial…

A: SOLUTION: Step 1: Vitamin C is also called ascorbic acid, is a water-soluble nutrient. The…

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.