How does DNA replicate itself? Your explanation (in essay form) should include the following terms: helicase, origins of replication, primase, DNA polymerase (I, II and III), leading strand, lagging strand, Okazaki fragment, DNA ligase, and topoisomerase.

How does DNA replicate itself? Your explanation (in essay form) should include the following terms: helicase, origins of replication, primase, DNA polymerase (I, II and III), leading strand, lagging strand, Okazaki fragment, DNA ligase, and topoisomerase.

Name: How does DNA replicate itself? Your explanation (in essay form) should
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Description: How does DNA replicate itself? Your explanation (in essay form) should include the following terms: helicase, origins of replication, primase, DNA polymerase (I, II and III), leading strand, lagging strand, Okazaki fragment, DNA ligase, and topoisome

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter21: Dna, Genes, And Biotechnology

Section: Chapter Questions

Problem 1RQ: Why is DNA replication called semiconservative?

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Which statement below best describes what these data might have demonstrated to Kornberg about the process of replication? CHOOSE ONE and explain the rationale behind your answer in a minimum of four sentences. A. Products of replication are DNA polymers. B. DNA Pol I-mediated replication is a high-fidelity (i.e., no mistakes) process C. DNA Pol III-mediated replication gives rise to two daughter strands, one which is made of only the original templates, and one of which is only newly synthesized polymer. D. In DNA, all 4 classes of nitrogenous bases are more or less equally represented E. A pairs with T and C pairs with G
The speed of DNA replication at a replication fork is about 100 nucleotides per second in human cells. What is the minimum number of origins of replication that a human cell must have if it is to replicate its DNA once every 24 hours?
besides DNA pol I and DNA pol III What are the roles of the other enzymes involved in replication and why they're necessary ?
Describe DNA replication. What are Okazaki fragments? Why does each chromosome have thousands of replication start sites instead of just one?
True or false: During DNA replication, the DNA template is read 3 ́ to 5 ́ by a DNA polymerase, as the DNA polymerase adds nucleotides to the growing strand 5 ́ to 3 ́?
Which is the odd one out ? explain how the rest are connected. primers dNTPs DNA polymerase complementary DNA reverse transcriptase helicase
What are the differences between In vitro and In vivo DNA replication? Please answer at your own words.
An investigator obtains a bacterial temperature-sensitive mutation that affects a step in the process of DNA replication at 42°C but not at 30°C. She grows the cells at 30°C and, upon shifting the temperature to 42°C, she discovers that Okazaki fragments accumulate in unusually large quantities. What is the likely target affected by the temperature-sensitive mutation? primase DNA polymerase III DNA helicase DNA Ligase DNA gyrase
The spontaneous loss of amino groups from adenine inDNA results in hypoxanthine, an uncommon base, oppositethymine. What combination of proteins could repair suchdamage?(A) nuclease, DNA polymerase, DNA ligase(B) telomerase, primase, DNA polymerase(C) telomerase, helicase, single-strand bindingprotein(D) DNA ligase, replication fork proteins, adenylylcyclase
Here are two strands of DNA. —————————————— DNA polymerase→ —————————————————————— The one on the bottom is a template strand, and the one on the top is being synthesized by DNA polymerase in the direction shown by the arrow. Label the 5′ and 3′ ends of the top and bottom strands.
Which statement about Okazaki fragments is true? Select one: a. DNA polymerase doesn’t need a primer to build these fragments b. They act as a primer that initiates DNA replication. c. They correct errors made during earlier phases of DNA replication. d. They are necessary because DNA polymerase can only build DNA in the 5’ to 3’ direction, so for one of the strands at each fork, the DNA polymerase can only buildaway from the fork. e. They prevent the ends of chromosomes from shortening with every replication.
Sketch a LARGE labeled figure showing one replication fork and the synthesis of one leading strand and two lagging strands of DNA in the replication bubble. Label the 5’ and 3’ ends of all DNA strands shown in your figure. Also label any DNA polymerases, DNA helicases, primases and primers. (For this question you may assume that lagging strands have not been joined.)