(i) (ii) (iii) Cumulative Hazard 0.20 0.15- 0.10 0.05 0 Telomere length --- Shortest Cancer incidence P<.001 20 - Middle Longest p 40 60 Follow-up, mo Figure 3 80 100 120 Based on your examination of Figure 3, infer why cancer incidence decreases with longer telomeres. Predict what happens to the telomere of cancer cells. Telomerase inhibitors have been developed to fight cancer. Would you expect these drugs to be beneficial to the population studied in Figure 3?

Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter17: Biotechnology And Genomics
Section: Chapter Questions
Problem 3VCQ: Figure 17.15 In 2011, the United States Preventative Services Task Force recommended against using...
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(b)
The following study (Figure 3) shows the cumulative cancer incidence of a
population for the time span (x-axis: follow-up months) studied.
(i)
(ii)
(iii)
Cumulative Hazard
0.20
0.15-
0.10-
0.05
0
Telomere length
- Shortest
- Middle
P<.001
Cancer incidence
20
Longest
40 60 80 100 120
Follow-up, mo
Figure 3
Based on your examination of Figure 3, infer why cancer incidence decreases
with longer telomeres.
Predict what happens to the telomere of cancer cells.
Telomerase inhibitors have been developed to fight cancer. Would you
expect these drugs to be beneficial to the population studied in Figure 3?
Transcribed Image Text:(b) The following study (Figure 3) shows the cumulative cancer incidence of a population for the time span (x-axis: follow-up months) studied. (i) (ii) (iii) Cumulative Hazard 0.20 0.15- 0.10- 0.05 0 Telomere length - Shortest - Middle P<.001 Cancer incidence 20 Longest 40 60 80 100 120 Follow-up, mo Figure 3 Based on your examination of Figure 3, infer why cancer incidence decreases with longer telomeres. Predict what happens to the telomere of cancer cells. Telomerase inhibitors have been developed to fight cancer. Would you expect these drugs to be beneficial to the population studied in Figure 3?
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