Given the following codons and their corresponding amino acids: UUU- Phenylalanine GAA- Glutamate CAA- Glutamine AAU-Asparagine AAC- Asn AAA- Lysine UCU-Serine GGA- Glycine ACC-Threonine AUG- Met/ START codon CCU- Proline GUU- Valine UAU- Tyrosine UAA- STOP AGG- Arginine AUU- Isoleucine CAU- Histidine GCU-Alanine UGU-Cysteir GAU-Asparti CUA- Leucine UGG-Tryptol CGU-Arginin Box 1: Show the mRNA sequence which codes for the short peptide, lys-ala-phe- leu. Include what should come before and after this short message. Don't leave any spaces between the letters. Box 2: Show the tRNA anticodon sequence that would line up with the mRNA strand from Box 1. Don't leave any spaces between the letters. Box 3 & 4: Show the DNA base sequence that would be found in the DNA double helix which carries the gene for this peptide. Give the coding strand sequence in Box 3 and template strand sequence in Box 4. Don't leave any spaces between the letters. Box 5: What if there was a frameshift at leucine (CTA)? A nucleotide cytosine was inserted directly after the first cytosine (on the template strand) to become (CCT). How would the amino acid sequence be altered? Would this alter translation? If so, how? Box 6: When the DNA was replicated which enzymes were responsible for this error? Give the names of the enzymes separated by a comma.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter30: Protein Synthesis
Section: Chapter Questions
Problem 6P
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Given the following codons and their corresponding amino acids:
UUU-Phenylalanine
GAA- Glutamate
CAA- Glutamine
AAU- Asparagine
AAC- Asn
AAA- Lysine
UCU- Serine
GGA-Glycine
ACC-Threonine
AUG- Met/ START
codon
CCU- Proline
GUU- Valine
UAU-Tyrosine
UAA- STOP
AGG- Arginine
AUU- Isoleucine
CAU- Histidine
GCU- Alanine
UGU-Cysteir
GAU-Asparti
CUA-Leucine
UGG-Tryptol
CGU-Arginin
Box 1: Show the mRNA sequence which codes for the short peptide, lys-ala-phe-
leu. Include what should come before and after this short message. Don't leave any
spaces between the letters.
Box 2: Show the tRNA anticodon sequence that would line up with the mRNA
strand from Box 1. Don't leave any spaces between the letters.
Box 3 & 4: Show the DNA base sequence that would be found in the DNA double
helix which carries the gene for this peptide. Give the coding strand sequence in Box
3 and template strand sequence in Box 4. Don't leave any spaces between the
letters.
Box 5: What if there was a frameshift at leucine (CTA)? A nucleotide cytosine was
inserted directly after the first cytosine (on the template strand) to become (CCT).
How would the amino acid sequence be altered? Would this alter translation? If so,
how?
Box 6: When the DNA was replicated which enzymes were responsible for this
error? Give the names of the enzymes separated by a comma.
Transcribed Image Text:Given the following codons and their corresponding amino acids: UUU-Phenylalanine GAA- Glutamate CAA- Glutamine AAU- Asparagine AAC- Asn AAA- Lysine UCU- Serine GGA-Glycine ACC-Threonine AUG- Met/ START codon CCU- Proline GUU- Valine UAU-Tyrosine UAA- STOP AGG- Arginine AUU- Isoleucine CAU- Histidine GCU- Alanine UGU-Cysteir GAU-Asparti CUA-Leucine UGG-Tryptol CGU-Arginin Box 1: Show the mRNA sequence which codes for the short peptide, lys-ala-phe- leu. Include what should come before and after this short message. Don't leave any spaces between the letters. Box 2: Show the tRNA anticodon sequence that would line up with the mRNA strand from Box 1. Don't leave any spaces between the letters. Box 3 & 4: Show the DNA base sequence that would be found in the DNA double helix which carries the gene for this peptide. Give the coding strand sequence in Box 3 and template strand sequence in Box 4. Don't leave any spaces between the letters. Box 5: What if there was a frameshift at leucine (CTA)? A nucleotide cytosine was inserted directly after the first cytosine (on the template strand) to become (CCT). How would the amino acid sequence be altered? Would this alter translation? If so, how? Box 6: When the DNA was replicated which enzymes were responsible for this error? Give the names of the enzymes separated by a comma.
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