If the 5’ splice site sequences changed from 5’GUAAGU 3’ to 5’ GUAUGU 3’, predict the effect of the sequence on U1 binding and u6 snRNP binding in an invitro protein binding assay.

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter13: An Introduction To Genetic Technology
Section: Chapter Questions
Problem 20QP: Analyzing Cloned Sequences A base change (A to T) is the mutational event that created the mutant...
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  1. If the 5’ splice site sequences changed from 5’GUAAGU 3’ to 5’ GUAUGU 3’, predict the effect of the sequence on U1 binding and u6 snRNP binding in an invitro protein binding assay.
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