Is the statement during fatty acid biosynthesis, the product detaches from fatty acid synthase complex when the chain length is 16 carbons, wrong or right?
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Is the statement during fatty acid biosynthesis, the product detaches from fatty acid synthase complex when the chain length is 16 carbons, wrong or right?
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- During fatty acid biosynthesis, is it correct that the product detaches from fatty acid synthase complex when the chain length is 16 carbons?The second step during elongation of fatty acid chain is catalyzed by B-ketoacyl reducatse. In which 2 ways is this reaction different from the corresponding reaction in fatty acid degradation?Is it true that beta-ketoacyl-ACP-reductase catalyzes the committed stepn in fatty acid biosynthesis?
- What would be the effect on fatty acid synthesis of a mutation in ATPcitrate lyase that reduces the enzyme’s activity? Explain.Consider the complete oxidation of a mixed TAG containing the following fatty acid residues:At carbon 1: cerotic acidAt carbon 2: heptadecanoic acidAt carbon 3: palmitoleic acid Draw the structure of the mixed TAG.We have stated that fatty acids cannot yield a net gain in carbohydrates in organisms that lack a glyoxalate pathway. Why can odd-chain fatty acids be thought to break this rule to a small extent?
- Is the statement during fatty acid biosynthesis, NADH is used as the reducing equivalent in the process wrong or right?If G6P is labeled at its C2 position, where will the label appear in the products of the pentose phosphate pathway?If phenylalanine was not an essential amino acid, would diet therapy (the elimination of phenylalanine from the diet) for PKU work? Do not just say yes or no. Give a short explanation for this hypothetical situation.
- Explain why people with a hereditary deficiency of carnitine acyltransferase II have muscle weakness. Why are the symptoms more severe during fasting?What is the smallest number of molecules of ATP and GTP consumed in the synthesis of a 200- residue protein, starting from amino acids? Assume that the hydrolysis of PP i is equivalent to the hydrolysis of ATP for this calculation.PLP is a cofactor for a number of enzymes involved in amino acid metabolism. Give an example of reaction in which PLP participates in cleavage of the a, b, and c bonds of an amino acid, as diagrammed in shown Fig.