Question
Asked Jan 17, 2019
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Label the figure to assess your knowledge of DNA replication.
Drag the appropriate labels to their respective targets
Reset] Help
Okazaki
fragment
DNA polymera
ase
DNA polymerase
Nucleotide
Leading strand
Replication fork
Stabilizing
proteins
Ligase
Primase
Helicase
Lagging strand
RNA primer
IIIN
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Label the figure to assess your knowledge of DNA replication. Drag the appropriate labels to their respective targets Reset] Help Okazaki fragment DNA polymera ase DNA polymerase Nucleotide Leading strand Replication fork Stabilizing proteins Ligase Primase Helicase Lagging strand RNA primer IIIN

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Step 1

The given diagram shows the replication of the DNA.

The DNA replication can be defined as a process, by which the existing double-stranded DNA is copied and produces two identical DNA strands.

For an easy understanding, the diagram is labeled with numbers 1 to 12 as shown in the figure.

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Step 2

During the DNA replication, the double strands get separated into two forming a replication fork. The new strand formed corresponding to the 5’-3’ strand of the DNA is known as the leading strand and the strand formed corresponding to the 3’ – 5 ’ strand is known as lagging strand. The single strand of the replication fork is stabilized with the help of the Single strand stabilizing proteins.  

The new strands are formed by the recruitments of the nucleotides. The nucleotides of the DNA have a deoxyribose sugar, nitrogenous base, and three phosphate groups. Depending on the nucleotide present on the original strand, a complementary nucleotide is added to the new strand.

Hence, the label 1 is replication fork, the label 2 is stabilizing protein, label 3 is nucleotide, and label 4 is leading strand.

Step 3

The recruitment of the nucleotides takes place with the help of DNA polymerase III. The DNA polymerase can work only in 5’-3’ direction. Hence, the nucleotides are added to the lagging strands appear in fragments. These fragments are known as Okazaki fragments.

The helicase is an enzyme, which unwinds the double-stranded DNA for the initiation of the replication.  The primase is an enzyme, which synthesizes the primer at the site of the replication; it serves as a starting point of the DNA replication. The primase...

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