nich snows tne specincity poCkets. Ine Si pocket nas a utamic acid in the bottom, the S2 pocket is small and drophobic, and the S,' pocket is deep and hydrophobic. uggest a 3-amino acid sequence that this protease would eave and indicate between which sites the peptide bond R2 R1 would be broken. S2 Which sequence would this protease cleave? Val-Lys-Phe

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter31: Completing The Protein Life Cycle: Folding, Processing, And Degradation
Section: Chapter Questions
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wnich snows tne specinicity pockets. The S pocket nas a
Ra
glutamic acid in the bottom, the S2 pocket is small and
hydrophobic, and the S,' pocket is deep and hydrophobic.
Suggest a 3-amino acid sequence that this protease would
R2
H
cleave and indicate between which sites the peptide bond
would be broken.
S2
Which sequence would this protease cleave?
Val-Lys-Phe
Phe-Lys-Val
Lys-Phe-Val
Val-Phe-Lys
Phe-Val-Lys
O Lys-Val-Phe
The peptide bond that is broken is between which sites?
O S2 and S,'
OS, and S,'
O S2 and S1
O S2 and S1, and S and S,'
IZ
Transcribed Image Text:<> wnich snows tne specinicity pockets. The S pocket nas a Ra glutamic acid in the bottom, the S2 pocket is small and hydrophobic, and the S,' pocket is deep and hydrophobic. Suggest a 3-amino acid sequence that this protease would R2 H cleave and indicate between which sites the peptide bond would be broken. S2 Which sequence would this protease cleave? Val-Lys-Phe Phe-Lys-Val Lys-Phe-Val Val-Phe-Lys Phe-Val-Lys O Lys-Val-Phe The peptide bond that is broken is between which sites? O S2 and S,' OS, and S,' O S2 and S1 O S2 and S1, and S and S,' IZ
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