но [1] KOH [2] CH31 'N. но но codeine morphine

Q: Scheme 2: Synthesis of a common antihistamine from benzaldehyde. Mg, ether 1. Ether 2. 1M HCI HBr…

A: Diphenhydramine is an antihistamine. Synthesis of antihistamine from benzaldehyde:

Q: Which of the following compounds is the most basic? A. p-methoxyaniline B. aniline C.…

A: As we know that aromatic amines are less basic than the alipahatic amine , because of resonance…

Q: Although codeine occurs in low concentration in the opium poppy, most of the codeine used in…

A: The given compound is morphine. We derive codeine from morphine by selective methylation method.

Q: Which electrophile is most likely to undergo a 1,2-hydride shift during an electrophilic aromatic…

A: In electrophilic aromatic substitution of benzene in presence of AlCl3. First of all the alkyl…

Q: Rank each set of compounds in order of increasing basicity.pyrrole, imidazole, 3-nitropyrrole

A: Basicity is the tendency of the substance to accept the protons or having a tendency to donate its…

Q: What is the most likely organic product of the exhaustive hydrolysis of PhCN?  A. benzoic acid   B.…

A: The question is based on the concept of organic reactions.   We have to identify the product formed…

Q: Arrange the following compounds in the increasing order of their reactivity in nucleophilic attack…

A: More the electrone deficiency on the carbonyl carbon  , more easily the attack of the nucleophilie…

Q: Identify compounds A and B, two synthetic intermediates in the 1979 synthesis of the plant growth…

A: Gibberellic acid is a hormone found in plants and fungi. It has a chemical formula as C19H22O6. It…

Q: Heating compound X with aqueous formaldehyde forms Y (C17H23NO), which has been converted to a…

A: Y has to be identified and how it is formed has to be explained

Q: Orsellinic acid, a common constituent of lichens, is synthesized from the condensation of acetyl…

A:

Q: Aziridines are heterocycles that contain an N atom in a three-membered ring. Like epoxides,…

A: Oseltamivir total synthesis concerns the total synthesis of the antiinfluenza drug oseltamivir…

Q: From what aldehyde or ketone could each of the following be prepared by reduction with NaBH4 or…

A:

Q: Rank the following from LEAST TO MOST reactive towards electrophilic aromatic substitution: 1.…

A: A question based on aromatic compounds that is to be accomplished.

Q: Which nitrogen atom in each compound is more basic?

A:

Q: In electrophilic aromatic substitution reactions a Iodine substituent on the aromatic ring is: a)…

A:

Q: Phenacetin is an analgesic compound having molecular formula C10H13NO2. Once a common component in…

A: From the IR spectrum a) It is observed that a peak around 1600 cm-1 shows that an amide group is…

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Q: Explain why trichloroacetic anhydride [(Cl3CCO)2O] is more reactive than acetic anhydride…

A: The nucleophiles are the type of substances that have tendency to donates the pair of electrons to…

Q: How is an amide converted to an anhydride? Water with strong acid → PCl5 → Carboxylic Acid PCl5 →…

A:

Q: Heating compound X with aqueous formaldehyde forms Y (C17H23NO),which has been converted to a…

A:

Q: What is the problem with running the following reaction? NH2 HNO3 H2SO4 It will result in multiple…

A:

Q: 3 3 H3C `Cl AlCl3

A: The Friedel craft acylation is the process of addition of acyl group to a compound

Q: a. Rank the following esters from most reactive to least reactive in the first slow step of a…

A: Observe the structures of the esters carefully. a) The order of reactivity of esters in the first…

Q: Cancer of the prostate is the second leading cause of cancer deaths among American males, exceeded…

A:

Q: Mustard gas, Cl¬CH2CH2¬S¬CH2CH2¬Cl, was used as a poisonous chemical agentin World War I. Mustard…

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Q: Acetanilide is less reactive than aniline toward eletrophilic substitution. Explain.

A:

Q: Enamines and imines are tautomers that contain N atoms. Draw a stepwise mechanism for the…

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A:

Q: Which of the following compounds is the most basic? A. p-nitroaniline B. p-chloroaniline C.…

A: Basicity depends on the stability of conjugate acid forms after accepting the proton.

Q: Which compounds give an SN2 substitution reaction on treatment with alcoholic NaSH? (b) Which…

A:

Q: Arrange the following compounds in an increasing order of their reactivity in nucleophilic addition…

A: Given, ethanal, propanal, propanone, butanone.

Q: Rank the following compounds in order of increasing basicity: I. p-nitroaniline…

A: The basicity of a compound is the tendency of the atom to donate its lone pair. More the electron…

Q: Rank the following compounds in order of increasing basicity: 1.p-nitroaniline I p-aminobenzaldehyde…

A:

Q: Which of the following acid derivatives can be hydrolyzed in water spontaneously without acid or…

A: Acid derivatives mainly gives Nucleophillic acyl substitution reaction, in which the group attached…

Q: The byproduct of the photo dimerization of benzophenone to benzopinacol is? OH hv Ph Ph OH Ph Ph Ph…

A: 1.) The photodimerization if benzophenone ho vis radical mechanism. We would write mechanism to…

Q: Aziridines are heterocycles that contain an N atom in a three-membered ring. Like epoxides,…

A: Oseltamivir total synthesis concerns the total synthesis of the antiinfluenza drug oseltamivir…

Q: OH OH CH

A:

Q: Rank the reactivity of the compounds below toward nucleophilic acyl substitution by writing the…

A: Interpretation: We have to arrange the given molecule in the order of their nucleophilic…

Q: In the following pairs of compounds, which is the most acidic? Benzoic acid and 4-nitrobenzoic acid…

A:

Q: 1. Rank and explain the following compounds in order of decreasing bacisity. Pyrole, Pyridine,…

A: 1) (1)Piperidine is the most basic. The N lone pair is in an sp3 hybrid orbital and there is no…

Q: (m) DMP, CH2CI2 PCC, CH2CI2 Pyridinium chlorochromate in methylene chloride solvent Aco OAc -OAc OH…

A:

Q: As described in Section 9.17, the leukotrienes, important components in the asthmatic response, are…

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Q: What is the intermédiate state of an acid-base catalysis during conversion of DHAP to GAP called,…

A:

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.