Н,о N: enamine imine

Q: Write the mechanism for the following reactions: 1. the acid-catalyzed hydrolysis of an imine to a…

A: Any chemical bond's cleavage gets catalyzed by using any protic acid through "nucleophilic…

Q: Amides are comparably unreactive to nucleophilic acyl substitution, yet the B-lactam antibiotics wn)…

A: Nitrogen is a better leaving group. Nitrogen donates more electron density into the carbonyl group.…

Q: 5. The following aminoketone can undergo an intramolecular reductive amination. Draw the expected…

A:

Q: In reactions with an aldehyde or ketone to form an imine or an enamine (Section 16.8)

A: Solution :      Aldehyde or ketone shows dehydration reaction with an amine to form imines. Imines…

Q: Enamines and imines are tautomers that contain N atoms. Draw a stepwise mechanism for the…

A: Imines are the nitrogen analouges of aldehydes and ketones containing a CN double bond instead of a…

Q: Although codeine occurs in low concentration in the opium poppy, most of the codeine used in…

A:

Q: Match the given product to its possible reaction. HO HO H₂N Choose... Choose... Aminolysis of…

A: Given,

Q: Which of the following is FALSE about the reaction below? +0₂N NH₂ Select one: Oa. It is initiated…

A:

Q: The reaction of a nitrile with an alcohol in the presence of a strong acid forms an N-substituted…

A: a. Hydrochloric acid protonate the R'OH group. The reaction proceeds with the elimination of water…

Q: When the rate constants for the hydrolysis of several morpholine enamines of para-substituted…

A: σ or  substituent constant :  electron-withdrawing substituents have positive substituent constants…

Q: An amide with an NH2 group can be dehydrated to a nitrile with thionyl chloride (SOCl2). Propose a…

A: The reaction is given as

Q: The first step in the mechanism for the reaction of an amine with a carboxylic acid to produce an…

A: The first step involved in the reaction between amine and carboxylic acid is given below

Q: 8) When pyridine is treated with a mixture of nitric and sulfuric acids, the major EAS product is:…

A:

Q: Select the most suitable set of reagents that can be used in reducing ethanamide CH;CONH2 to…

A: Degradation of amide group to primary amine using Br2 and alkali is called as Hoffmann Bromamide…

Q: Consider the following reaction schemes involving the reaction of an imine with an organolithium…

A: Lithium halogen exchange reaction :

Q: Identify M and N in the following reaction sequence, two steps in the original synthesis of the…

A: The given reaction is represented as follows:

Q: Draw the products that result from each step in the synthesis of m-bromoaniline. HNO3, H2SO4 Br2,…

A: Step 1: The reaction of benzene with a mixture of conc. HNO3 and conc. H2SO4 is Nitration reaction (…

Q: Cardiolipins are found in heart muscles. Draw the products formed when a cardiolipin undergoes…

A: Cardiolipins are present in heart muscles. The structure of the cardiolipins contains ester and…

Q: Direct alkylation of D by treatment with one equivalent of LDA and CH3I does not form ibuprofen.…

A:

Q: Which of the following functional groups will react faster and at lower conditions to a nucleophilic…

A: Given Choices  a. Carboxylic acid  b. Nitrile c. Acyl Halide  d Ester Functional Group will react…

Q: 1. НаNNH2, mild acid 2. КОН, Н20, heat 1. LDA 2. 3. Н,О, н* HCN KCN

A: Organic synthesis involves the process of preparation, isolation and characterization of organic…

Q: Identify the reactions needed to prepare A) (1) Acetyl chloride, (2) LIAIH4, (3) Benzyl bromide B)…

A: N-benzyl-N-methylbutylamine from 1-aminobutane can be synthesized by using = B) (1)…

Q: 2. Will the following reaction occur as written? HO, NH H2N cat. H2SO4 A) Yes, after initial…

A: This reaction is ring opening of lactam compound in the presence of acid catalyst. But this reaction…

Q: Below is one of the reactions used in the synthesis of lopinavir. What type of reaction is this? H…

A: In the given transformation NaOH is acting as a base and THF is solvent.

Q: Reduction of an alkyl azide results in the formation of —-. A. an imine B. an oxime C. a tertiary…

A: Alkyl azide have general formula R-N3

Q: What results when dimethylsulfide is treated with methyl iodide? 1) CH,I 2)- NH 3) -H A. B. C. D.

A: The reaction taking place is given as,

Q: What starting materials are needed to prepare 2-methylhexanoic acid [CH3CH2CH2CH2CH(CH3)COOH] using…

A: Given monoalkylmalonic ester is required to prepare 2-methylhexanoic acid.

Q: `OR OR Benzoate esters can undergo either acid- or base-catalyzed hydrolysis as shown below. HOR +…

A: The reaction is the hydrolysis of benzoate esters.

Q: Enamines and imines are tautomers that contain N atoms. Draw astepwise mechanism for the…

A: The mechanism of the above reaction is as given below:

Q: „CHO NH3 H2. Ni A -H20 60 °C, 90 atm CI

A: Since the N in NH3 is having lone pair electron and C attached to O in the benzene reactant is…

Q: Draw the mechanism for the reaction of butanone with NaBH4 followed by the addition of aqueous acid.

A: NaBH4 provides hydride ion, H-

Q: Draw the mechanism form the formation of the imine from the aldehyde below. HN + H20 (18-18) (+ Z…

A:

Q: Predict the products obtained from the reaction of triolein with the following reagents.(a) NaOH in…

A: a.

Q: Consider the following reaction schemes involving the reaction of an imine with an organolithium…

A: We have find out the reaction of an imine with an organolithium compound.

Q: What starting materials are needed to prepare 2-methylhexanoic acid[CH3CH2CH2CH2CH(CH3)COOH] using a…

A: Malonic ester is a chemical reagent which is mainly used to convert alkyl halides to carboxylic…

Q: Draw the mechanism for the reaction of benzyl nitrile with methyl Grignard followed by an acid…

A: Nucleophilic addition reaction followed by acid base reaction gives the hydrolysis product.

Q: OH HNO2 NH2 H2N `NH2 OH 4,5-diaminopyrimidines 4-hydroxypyrazolo(3,4-d)pyrimidine aka: Allopurinol

A:

Q: :NH2 NH3 NH, CN hydrolysis CN R coo e-amino acids can be prepared by the Strecker zpathesis, a…

A: Strecker's synthesis is widely used in the production of o-aminonitriles. It consists of two steps…

Q: Consider the following reaction schemes involving the reaction of an imine with an organolithium…

A: n-BuLi being a non-bulky organolithium can undergo halogen exchange as well as a nucleophile that…

Q: Cardiolipins are found in heart muscles. Draw the products formed when a cardiolipin undergoes…

A: The mechanism is as follows:

Q: An amide with an NH2 group can be dehydrated to a nitrile with thionyl chloride (SOCl2). Propose a…

A: Thionyl chloride when reacts with 1° amide, a nitrile can be produced. A four step mechanism can be…

Q: Q 9.34: Which of the following is not an effective base for deprotonating a terminal alkyne? A…

A: (B) Potassium hydroxide. KOH is not an effective base for deprotonating a terminal alkyne because it…

Q: What product is obtained from the reaction of N,N-dimethylaniline with nitrous acid? A.…

A: The product obtained from the reaction of N,N-dimethylaniline with nitrous acid is given below.

Q: 5. Although codeine occurs in low concentration in the opium poppy, most of the codeine used in…

A: In reaction, reagent KOH is base which abstracts acidic proton whereas alkyl part of alkyl halide…

Q: Which of the following reaction or reagent does not produce an amine molecule? A. Curtius…

A: The given reactions are A. Curtius rearrangement B. Reaction of oximes with metallic sodium in…

Q: 2. Draw the structure of the products that will be formed when aniline reacts with nitrous acid at 5…

A:

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.