Nucleotide Position 10 15 Sequence 1. ... T CT GGATCATCACAT. .. Sequence 2. Sequence 3. Sequence 4. Sequence 5. ACA G C AT CATTAC GT... T C AGG AT CAT TACAT. .. T C A GG ATCAT TACAT. .. ACA GC ATCAT TACGT. .. T C T G GATCATCACAT. .. T C AGGATCATTACAT. .. Sequence 6. . Sequence 7. Sequence 8. .. ACAG CATCATTAC GT. ..

Knock out mice that are mutant for a gene product X die. Variants of the X gene that were reintroduced through homologous recombination indicate that variant proteins that lack the C-terminal region of the protein cannot rescue the lethality (did not allow them to live), and always localized to the cytoplasm. Those that retained the C-terminal region rescued the lethality (conferred viability!) and were consistently localized within the nucleus. RNA-seq analysis of the mutant cells vs the wild-type cells indicated that the expression of many genes that are essential for neural function was reduced in the knock-out mutant cells. The N-terminal region of Protein X is 100% conserved between mouse and humans at both the amino acid and the nucleotide level. The predicted mouse mRNA sequence is shown below where the AUG corresponds to the translational start site (AUG). 5’-AUGUUUACAGAGGGGAAU... -3’     d) What motif could be present to direct this protein to its correct destination?  e)…

In Anopheline mosquitoes an inversion associated with resistance to desiccation involves the centromere. These inversions are _______.

A options, B options are LacOc lacZ+ lacY+, lacI+ lac0+ lacY+, lacI+ lacZ+ lacY-, none would restore