One of the following is false: a. Glycosylated HbA has glucose attached to N- terminal of beta subunits. b. HbAlc is a glycoprotein.
Q: Which of the following statements are correct about protein folding (select all that appy)? A.…
A: Protein folding is the physical process by which a protein folds into its functional…
Q: Phosphorylation is a common covalent modification of proteins in all forms of life, which leads to…
A: Phosphorylation refers to the biochemical process that involves the addition of phosphate to an…
Q: What two processes ensure that the correct amino acidis added to a growing polypeptide chain?
A: The tRNA is a transfer RNA. It reads the nucleotide present on the mRNA and translates that mRNA…
Q: Are the enzyme ADH and ALDH simple or conjugated proteins, and how do you know this?
A: ENZYMES- Enzymes are highly specialized proteins that act as a catalyst in the biological system,…
Q: Which derivative of folate is a reactant in the conversion of (a) glycine into serine? (b)…
A: Introduction: Proteins are biomolecules that consist of one or more long chains of amino acid…
Q: In the deoxy state of HB, which of the following does not occur? a) An inter-chain salt bridge…
A: Because hydrogen bonds and salt bridges, or ion-pair bonds, stabilize the deoxygenated form of…
Q: Protein X is normally used to transport sugar into cells, so the cell can break down the sugar and…
A: Protein folding is the physical process by which a protein chain acquires its native 3-dimensional…
Q: Are the amino acid residues at the active site need to be in close proximity to one another…
A: Enzymes are the catalysts that catalyze biochemical reactions. These are proteinaceous in nature as…
Q: Lactose permease, a protein of E. coli, is composed of a singlepolypeptide that is 417 amino acids…
A: Translation is the process by which the protein is synthesized by reading the codons in mRNA. The…
Q: The amino acid tyrosine contains a phenolic R-group and has pKa values of 2.2, 9.0, and 10.2. A…
A: tyrosine or L-tyrosine is one of the 20 standard amino acids that are used by cells to synthesize…
Q: Describe the three main classes of glycoproteins and explain their biochemical roles.
A: Introduction Glycoproteins are proteins that contain carbohydrates attached to amino acid…
Q: In sickle cell anemia, an inherited form of anemia in which the hemoglobin distorts the red blood…
A: The mutation that alters the codon that codes for a specific amino acid is called missense mutation.…
Q: What makes protein phosphorylation so valuable in regulating protein function that its use is…
A: Proteins are modified post-translationally via several covalent and non-covalent modifications.…
Q: Identify the parts of the heterotrimeric G-protein shown in the image. B
A: Introduction :- G proteins, also known as guanine nucleotide-binding proteins, are a group of…
Q: Illustrate the pathways to synthesize the following aminoacids:a. glutamineb. serinec. arginined.…
A: Introduction: The macromolecules that contain two functional groups that are amine and carboxyl are…
Q: What are the possible phosphorylation sites in a target protein?
A: Protein phosphorylation It is defined as the process of reversible post translational modification…
Q: Why "cellulose is composed of a long, branced chain of B-glucose subunits" is false?
A: Introduction Polysaccharides, also known as polycarbohydrates, are the most common type of…
Q: What are some advantages for a glycoprotein in having a large number of N-glycosylation sites?
A: Glycoproteins are a type of conjugated proteins. They have carbohydrates(oligosaccharides)…
Q: A protease is an enzyme that catalyzes the hydrolysis of the peptide bonds of target proteins. How…
A: A peptide bond is an amide type of covalent chemical bond linking two consecutive alpha amino acids…
Q: In the Procedure, you were instructed to use your original mixture of phycocyanin and 0.10 M sodium…
A: Phycocyanin: It is a blue color pigment found mainly in cyanobacteria and some algae and is…
Q: What functions would you expect to be served by residues such as (a) phenylalanine at the protein…
A: Protein structures are formed by the three-dimensional arrangement of amino acids in a protein…
Q: HiCan you help me solve this question?
A: a) Cysteine is a non-essential sulfur-containing amino acid in humans, related to cystine, Cysteine…
Q: What is the oligosaccharide-transferring moiety in N-link glycosylation?
A: N-linked glycosylation, is the attachment of an oligosaccharide, to a nitrogen atom mostly of the…
Q: Tyrosine is a nonessential amino acid in humans. Under what circumstance would it become an…
A: Amino acids are biomolecules serving as the building blocks of proteins. These have a carboxylic…
Q: Proteins are essential to most processes in the human body. Given your understanding of the M phase…
A: Cell Cycle and Phases Of Cell Cycle ---- The ordered sequences of events which takes place in the…
Q: Is the statement "elongation is the process of introducing double bond in fatty acid", correct?
A: Fatty acid Elongation is the process in which to make fatty acids longer than 16 carbons occurs in…
Q: Is the statement: "There is energy requirement for every amino acid added in a growing polypeptide…
A: Amino acids are the building blocks of proteins. The synthesis of polypeptide chain occur during…
Q: Consider the image of the attached protein. Now imagine you have a proteolytic enzyme that cleaves…
A: The mentioned proteolytic enzyme cleaves the peptide-bonds on the C-terminal sides of basic amino…
Q: Define the following terms: a. intrinsically disordered protein b. intrinsically disordered region…
A: Note: Since you have posted a question with multiple subparts, we will solve the first three…
Q: In a disease known as phenylketonuria, a person is not able to break down the particular amino acid…
A: Phenylketonuria: Phenylketonuria (also referred as “PKU”) is a unique genetic condition that causes…
Q: Which of the following might cause the denaturation of a protein? Select all that apply. A.…
A: PROTEIN STRUCTURE:- Protein structure is a 3 D Structure which forms 4 structures: 1)PRIMARY…
Q: Give an example of a protein containing primarily alphahelices. Is this a fibrous or globular…
A: α-helix structure of a protein is a secondary structure of proteins where it forms a hydrogen bond…
Q: Define the following terms: a. sugar code b. lectin c. glycoform d. glycome e. microheterogeneity
A: Glycoproteins are the proteins that are attracted to a sugar moiety majorly oligosaccharide. These…
Q: List three purposes served by protein turnover.
A: Proteins are composed of amino acids. An amino acid consists of an amino group (-NH2), a carboxylic…
Q: In the deoxy state of HB, which of the following does not occur? O An intra-chain salt bridge…
A: Hemoglobin is an oligomeric conjugated protein with four peptide chains joined by a…
Q: Sweet proteins. List the key classes of glycoproteins, their defining characteristics, and their…
A: Glycoproteins are known as specialized proteins that are composed of oligosaccharide chains i.e,…
Q: Valine is an amino acid with a nonpolar side chain and serine is one with a polar side chain. Draw…
A: Amino acids are building blocks of proteins. Based on the polarity amino acids are grouped into four…
Q: A. What change should disrupt the interaction between proteins 1 and 2 the most? Why? B. What…
A: Introduction: Proteins are the polymers of L-α-amino acids. Proteins plays an important role in the…
Q: Suppose that there is a protein consisting of two polypeptide chains with the given sequences in the…
A: Hi! Thanks for your question. As you have posted multiple questions, we are answering the first…
Q: Draw the formula of each of the following: a. Aspartic acid-histidine-tryptophan b.…
A: Hi! Thanks for your question. As you have posted multiple questions we are answering only the first…
Q: Why is it not recommended to use reconstituted or evaporated milk? Why is full cream milk suggested…
A: The United States Public Health Service defines Recombined milk or Reconstituted milk as an…
Q: What factors affect denaturation and refolding of proteins
A: Denaturation(unfolding) is the process in which protein loses the three-dimensional structure by…
Q: . Theoretical and experimental measurements show that in many cases, the contributions of ionic and…
A: The amino acid sequence of the polypeptide/protein is the primary structure of the protein. The…
Q: Certain enzymes catalyze the covalent linkage of an acetyl group to lysine amino acids as shown…
A: Options 3 and 4 are correct. Acetylation changes tertiary structure of protein and partner protein…
Q: Unbranched homopolymer of N-acetyl glucosamine is : 1.Cellulose 2.Chitin 3.Curcumin 4.Concanavalin A
A: Ans: N-acetyl glucosamine: The glcosamine and acetic bonded by amide linkage is referred to as…
Q: Branched-chain amino acids are important in metabolic processes for all of the following reasons…
A: Amino acids are generally used to make protein and poly peptide chain
Q: Are all the amino-acids soluble in water? Explain why?
A: Biomolecules are organic molecules present in living organisms. There are mainly four major…
Q: Can you please describe the specific components that each of these structures are comprised of (…
A: Proteins are the biomolecules which are made up of amino acids. Amino acids are joined together with…
Q: Draw the Fischer Projection, Haworth and Chair conformation for D-Glucose
A: Carbohydrate sugars are present in several forms. These conformations are either open in a chain…
Step by step
Solved in 3 steps
- A new oxygen transport protein that exhibits cooperative binding has been isolated and is beingstudied in the lab. Calculate the KD value if Y = 0.76 when pO2 = 18 torr (assume n = 2.5). Howdoes this compare to the KD value for hemoglobin? Does this protein bind more or less tightly tooxygen compared to hemoglobin?One molecule of 2,3-bisphosphoglycerate (BPG) binds to one molecule of haemoglobin (Hb) in a central cavity of the haemoglobin molecule. Is the interaction between BPG and Hb stronger or weaker than it would be if BPG were bound to the surface of the protein instead? Explain your answer.Highly active muscles generate lactic acid by respiration so fast that the blood bassing through the muscle actually experiences a drop in pH from 7.4 to 7.2. Under these conditions, hemoglobin releases about 10% more O2 than it does at pH 7.4. Explain.
- hi there you have said Microcytic anemia could be caused due to both iron deficiency anemia and thalassemia. could you expalin in detail why and how. With the a of diagram Along with mechanims.Pathological changes in the liver and brain were found in a 27-year-old patient. A diagnosis was Wilson's disease.a) What protein deficiency is observed? What class of globulin does it belong to?b) What is the biological role of this proteinc) The exchange of which trace element is disturbed under these conditions and how will its content in blood plasma and urine change?Sickle-cell hemoglobin (HbS) differs from normal human adult hemoglobin (HbA) by a single mutational change, Glu6 S Val, which causes the HbS molecules to aggregate under proper conditions. Under certain conditions, the HbS filaments that form at body temperature disaggregate when the temperature is lowered to 0°C. Explain.
- One molecule of 2,3-BPG binds to one tetramer of hemoglobin in a central cavity of the hemoglobin molecule. Is the interaction between BPG and hemoglobin stronger or weaker than it would be if BPG bound to the surface of the protein instead? Explain your answer (hint: think about how these different situations affect the dielectric constant). (Please provide clear and sufficient explanation for the question, thank you!)In an experiment, hemoglobin is dissociated in a buffer and a subunit is isolated to study for its oxygen binding affinity. (i) What is the shape of the oxygen dissociation curve is expected in the experiment?Explain why. (ii) Is the Km of the isolated subunit higher or lower than the Km of an intact hemoglobin?Hemoglobin (Hb) is a blood protein that is responsible for transporting oxygen. It can exist in the protonated form as HbH*. The binding of oxygen can be represented by the simplified equation HbH+ + 02 > ABO2 + Ht A. Excessive vomiting may lead to metabolic alkalosis, in which [H2O*] in blood decreases. How does this condition affect the ability of Hb to transport O2? B.Diabetes mellitus may lead to metabolic acidosis, in which [HgO*] in blood How does this condition affect the ability of Hb to transport O?
- Given: Factor VIIa is a man-made protein analog to Factor VII, which is involved in coagulation. (Answer a, b, and c)a. Identify both a competitive and non-competitive inhibitor for Factor VIIa b. Draw a graph showing how both of these molecules will change the Velocity/[S] graph, and explain why this is the case. c. What would a graph look like if both inhibitors were added?A crocodile, which can remain underwater without breathing for up to 1 hour drowns its air-breathing prey, then dines at its leisure. An adaptation that aids the crocodile in doing so is that it can utilize virtually 100% of the O2 in its blood whereas humans, for example, can only extract about 65% of the O2 in their blood. Crocodile Hb does not bind BPG. However, crocodile deoxyHb preferentially binds HCO3-. How does this help the crocodile obtain its dinner? Please help explain why/if this is the answer, thank you! As CO2 concentrations increase so will the concentration of HCO3-. The HCO3- preferentially binds to the crocodile's deoxyhemoglobin, which allosterically prompts the hemoglobin to assume the deoxy conformation and thus release its O2.Apohemoglobin (apoHb) is a dimeric globular protein with two vacant heme‐binding. The preparationof apoHb is based on partial hemoglobin (Hb) unfolding to facilitate heme extraction into an organic solvent. What is an appropriate method for removing the heme? a. An acidic buffer to protonate the His axial ligand in the presence of ureaas the denaturing agent. b. An acidic buffer to protonate the His axial ligand in the presence of mercatoethanol as the denaturing agent. c. A basic buffer to deprotonate the His axial ligand in the presence of ureaas the denaturing agent. d. An basic buffer to protonate the His axial ligand in the presence of mercatoethanol as the denaturing agent.