Operon The lac operon (a) Absence of lactose laco RNA polymerase operator Structural genes Regulator gene (lacl) lacz lacY lacA lacP Transcription and translation No transcription Active regulator protein (repressor) O In the absence of lactose, the regulator protein (a repressor) binds to the operator and inhibits transcription. laco RNA operator (b) Presence of lactose polymerase Transcription and translation Transcription and translation Active regulator protein .which then binds to the regulator protein, making the protein inactive. 4 The regulator protein cannot bind to the operator,. 3.and the structural genes are transcribed and translated. Inactive regulator protein (repressor) Enzymes B-Galactosidase Permease Transacetylase Allolactose Glucose 2 When lactose is present, some of It is converted into allolactose,. 16.7 The la. operon regulates lactose metabolism. BGalactosidase Galactose Lactose

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter10: From Proteins To Phenotypes
Section: Chapter Questions
Problem 21QP: Transcriptional regulators are proteins that bind to promoters (the 5-flanking regions of genes) to...
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Examine Figure 16.7. What would be the effect of a drug that altered the structure of allolactose so that it was unable to bind to the regulator protein?

Operon
The lac operon
(a) Absence of lactose
laco
RNA
polymerase
operator
Structural genes
Regulator
gene (lacl)
lacz
lacY
lacA
lacP
Transcription
and translation
No transcription
Active regulator
protein (repressor)
O In the absence of lactose, the regulator
protein (a repressor) binds to the
operator and inhibits transcription.
laco
RNA
operator
(b) Presence of lactose
polymerase
Transcription
and translation
Transcription
and translation
Active regulator
protein
.which then binds
to the regulator protein,
making the protein inactive.
4 The regulator
protein cannot bind
to the operator,.
3.and the structural
genes are transcribed
and translated.
Inactive regulator
protein (repressor)
Enzymes
B-Galactosidase Permease Transacetylase
Allolactose
Glucose
2 When lactose is present, some of
It is converted into allolactose,.
16.7 The la. operon regulates lactose metabolism.
BGalactosidase
Galactose
Lactose
Transcribed Image Text:Operon The lac operon (a) Absence of lactose laco RNA polymerase operator Structural genes Regulator gene (lacl) lacz lacY lacA lacP Transcription and translation No transcription Active regulator protein (repressor) O In the absence of lactose, the regulator protein (a repressor) binds to the operator and inhibits transcription. laco RNA operator (b) Presence of lactose polymerase Transcription and translation Transcription and translation Active regulator protein .which then binds to the regulator protein, making the protein inactive. 4 The regulator protein cannot bind to the operator,. 3.and the structural genes are transcribed and translated. Inactive regulator protein (repressor) Enzymes B-Galactosidase Permease Transacetylase Allolactose Glucose 2 When lactose is present, some of It is converted into allolactose,. 16.7 The la. operon regulates lactose metabolism. BGalactosidase Galactose Lactose
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