Oxaloacetate can be directly converted to [PEP/glucose/citrate/malate] in the process of gluconeogenesis. Oxaloacetate can be directly converted to [PEP/glucose/citrate/ malate] upon condensation with acetyl-CoA. Oxaloacetate can be directly converted to [PEP/glucose/citrate/malate] by a reversible enzyme in the citric acid cycle. Oxaloacetate, via many enzymes, is an important source of [PEP/glucose/citrate/malate] in the liver for tissues that rely on carbohydrates for the fuel source. help fill in the blanks

Oxaloacetate can be directly converted to [PEP/glucose/citrate/malate] in the process of gluconeogenesis. Oxaloacetate can be directly converted to [PEP/glucose/citrate/ malate] upon condensation with acetyl-CoA. Oxaloacetate can be directly converted to [PEP/glucose/citrate/malate] by a reversible enzyme in the citric acid cycle. Oxaloacetate, via many enzymes, is an important source of [PEP/glucose/citrate/malate] in the liver for tissues that rely on carbohydrates for the fuel source. help fill in the blanks

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter19: The Tricarboxylic Acid Cycle

Section: Chapter Questions

Problem 22P: Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is...

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Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is inhibited byÂ· NIADH. Pyruvate dehydrogenase is inhibited by AÎ¤Î¡. Citrate synthase is inhibited by NADH. Succinyl-CoA activates citrate synthase. Acetyl-CoA activates pyruvate carboxylase.
Which of the following is NOT a component of the pyruvate dehydrogenase complex? a. dihydrolipoyl dehydrogenase b. dihydrolipoyl transacetylase c. pyruvate dehydrogenase d. dihydrolipoyl catalase
The rate limiting and committed step of the pentose phosphate pathway is catalyzed by which of the following enzymes? A. Glucose-6-phosphate dehydrogenase B. Hexokinase C. 6-Phosphogluconate dehydrogenase D. Transketolase
Two carbon atoms are fed into the citric acid cycle as acetyl-CoA. In what form are two carbon atoms removed from the cycle?
The glycerol derived from lipolysis of triacylglycerols is converted into glyceraldehyde 3-phosphate, which then enters into step 6 of the glycolysis pathway. What further transformations are necessary to convert glyceraldehyde 3-phosphate into pyruvate?
Which of the following citric acid cycle enzymes catalyzes substrate-level phosphorylation? A) isocitrate dehydrogenase B) α-ketoglutarate dehydrogenase C) succinyl CoA synthetase D) succinate dehydrogenase E) malate dehydrogenase
Which of the following is most likely to cause accumulation of acetyl CoA? Group of answer choices There is not enough oxaloacetate present to run the citric acid cycle Increase activity of pyruvate dehydrogenase kinase Increased fatty acid synthesis Increased citrate synthase activity When fluoroacetate (an analog of acetate) is added to the mitochondria, it causes build up of fluorocitrate. Which of the following is most likely to be true? Group of answer choices Fluoroacetate cannot be converted to fluoroacetyl CoA Fluoroacetyl CoA cannot be combined with oxaloacetate to enter the citric acid cycle Addition of fluoroacetate will cause an increase in isocitrate Aconitase cannot use fluorocitrate as a substrate
All of the following enzymes catalyze a committed step EXCEPT: HMG-CoA reductase Fatty acyl-CoA synthetase Acetyl-CoA carboxylase I Pyruvate dehydrogenase complex All of the above enzymes catalyze a committed step The brain can directly use all of the following chemicals as energy source EXCEPT: Acetoacetate b-hydroxybutyrate Glucose Fatty acids All of the above can directly be used by the brain as energy source
How many acetyl CoA molecules can be produced during the complete β-oxidation of this fatty acid?
Name four amino acids that can be converted directly (in one step) into pyruvate or a citric acid cycle intermediate, and name the intermediate formed from each.
alpha-ketoglutarate dehydrogenase will do which of the following: Select one: a. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide b. Succinate is oxidized to become fumarate forming FADH2 c. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SH d. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) e. Malate is oxidized to become oxaloacetate forming NADH f. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH g. Citrate is rearranged to become Isocitrate h. Fumarate is combined with water to become Malate i. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH
The same reactions that were seen in the process of converting pyruvate to acetyl-S-CoA, occur in step ____ of the citric acid cycle as ____________ is converted to _________________.