Pathogens produce several types of proteins that can inhibit complement activation. The importance of complement activation as an innate immune defense against infections is illustrated by: The evolution of complement avoidance strategies by many pathogens The large number of proteins involved in the complement pathway The large number of complement regulatory pathways expressed by the host The existence of three different mechanisms for initiating complement activation The ability of the membrane attack complex to lyse some pathogens

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter17: Genes And The Immune System
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Problem 2QP: The Complement System Kills Microorganisms The complement system supplements the inflammatory...
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Pathogens produce several types of proteins that can inhibit complement activation. The importance of complement activation as an innate immune defense against infections is illustrated by:

  1. The evolution of complement avoidance strategies by many pathogens
  2. The large number of proteins involved in the complement pathway
  3. The large number of complement regulatory pathways expressed by the host
  4. The existence of three different mechanisms for initiating complement activation
  5. The ability of the membrane attack complex to lyse some pathogens
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