PRDM9 recruits SPO11, a topoisomerase type II like protein, to induce DNA double strand breaks. Illustrate and explain how SPO11 releases SPO11-linked oligonucleotides.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter28: Dna Metabolism: Replication, Recombination, And Repair
Section: Chapter Questions
Problem 9P: Heteroduplex DNA Formation in Recombination From the information in Figures 28.17 and 28.18, diagram...
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PRDM9 recruits SPO11, a topoisomerase type II like protein, to induce DNA double
strand breaks.
Illustrate
Illustrate
and explain
and
explain how SPO11 releases SPO11-linked
oligonucleotides.
Transcribed Image Text:PRDM9 recruits SPO11, a topoisomerase type II like protein, to induce DNA double strand breaks. Illustrate Illustrate and explain and explain how SPO11 releases SPO11-linked oligonucleotides.
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