reactant: 0.400g of p-amionphenol (MW=109.1) 0.450 ml of acetic anhyride (mw= 102.1 d= 1.08 ml) product: acetaminophen mw = 151.2 Calculate atom economy of the reaction. Calculate theoretical yield (in gram). Calculate the mass efficiency of the process (78% actual yield). Calculate the E-factor of the process (78% actual yield).

Principles of Instrumental Analysis
7th Edition
ISBN:9781305577213
Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Chapter11: Atomic Mass Spectrometry
Section: Chapter Questions
Problem 11.10QAP
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reactant:

0.400g of p-amionphenol (MW=109.1)

0.450 ml of acetic anhyride (mw= 102.1 d= 1.08 ml)

product:

acetaminophen mw = 151.2

  1. Calculate atom economy of the reaction.
  2. Calculate theoretical yield (in gram).
  3. Calculate the mass efficiency of the process (78% actual yield).
  4. Calculate the E-factor of the process (78% actual yield).
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