Segment of DNA SGCTAACCTGATCGCCGGTATT 3'CGATTGGACTAGCGGCCATAAS 3' 1. Transcribe and translate the above segment of DNA. 2. A point mutation occurs in the above segment of DNA. Nucleotide #14 is substituted by a nucleotide containing cytosine. Determine the sequence o amino acids in the polypeptide chain. Show all your work. Is there any vi: effect of the mutation, that is, is it a silent mutation? 3. The DNA segment above is mutated at nucleotide #12. The new nucleotide contains adenine. Transcríbe and translate the new DNA segment. What en if any, does this have on the protein sequence? Explain

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Chapter6: Dna Structure And Function
Section: Chapter Questions
Problem 1DID
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Use the bottom strand in question 1 and use the bottom strand in question 4
DNA MUTATIONS
Use the following information to answer the next three questions.
Segment of DNA
SGCTAACCTGATCGCCGGTATT 3
3'CGATTGGACTAGCGGCCATAAS
1. Transcribe and translate the above segment of DNA.
2. A point mutation occurs in the above segment of DNA. Nucleotide #14 is
substituted by a nucleotide containing cytosine. Determine the sequence of
amino acids in the polypeptide chain. Show all your work. Is there any visible
effect of the mutation, that is, is it a silent mutation?
3. The DNA segment above is mutated at nucleotide #12. The new nucleotide
contains adenine. Transcribe and translate the new DNA segment. What effect,
if any, does this have on the protein sequence? Explain.
Use the following information to answer the next three questions.
Segment of DNA
STGCAAATTTGTC 3°
3'
ACGTTTAAACAG *
4. Transcribe and translate the above segment of DNA.
5. A point mutation occurs in the above segment of DNA. Nucleotide #2 is
deleted. Determine the sequence of amino acids in the polypeptide chain.
Show all your work. Is there any visible effect of the mutation, that is, is it a
silent mutation?
6. A nucleotide containing thymine is inserted between nucleotides #7 and #8.
Transcribe and translate the new DNA segment. What effect, if any, does this
have on the protein sequence? Explain.
Transcribed Image Text:DNA MUTATIONS Use the following information to answer the next three questions. Segment of DNA SGCTAACCTGATCGCCGGTATT 3 3'CGATTGGACTAGCGGCCATAAS 1. Transcribe and translate the above segment of DNA. 2. A point mutation occurs in the above segment of DNA. Nucleotide #14 is substituted by a nucleotide containing cytosine. Determine the sequence of amino acids in the polypeptide chain. Show all your work. Is there any visible effect of the mutation, that is, is it a silent mutation? 3. The DNA segment above is mutated at nucleotide #12. The new nucleotide contains adenine. Transcribe and translate the new DNA segment. What effect, if any, does this have on the protein sequence? Explain. Use the following information to answer the next three questions. Segment of DNA STGCAAATTTGTC 3° 3' ACGTTTAAACAG * 4. Transcribe and translate the above segment of DNA. 5. A point mutation occurs in the above segment of DNA. Nucleotide #2 is deleted. Determine the sequence of amino acids in the polypeptide chain. Show all your work. Is there any visible effect of the mutation, that is, is it a silent mutation? 6. A nucleotide containing thymine is inserted between nucleotides #7 and #8. Transcribe and translate the new DNA segment. What effect, if any, does this have on the protein sequence? Explain.
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