Сно сно CH,OH Fo но H- HO- H- Phosphorogluco- isomerase Phosphofructo- kinase Нехоkinase но H- но -OH АТР - ADP H- -он H. OH он H- -он H- -он Via H. OH OH АТР ADP CH,OH CH,OPO, CH,OPO,2 но- Glucose A CH,OPO,2 Fo CH;OPO, Fo CH,OH Fructose но H- biphosphate D HO- HPO, / NAD+/ Glyceraldehyde 3- phosphate dehydrogenase aldolase Triose VT phosphate isomerase сно н он E CH,OPO, HO- CH,OPO, O OPO, Via с он CH,OPO, H- он -он CH,OPO, G F OPO, of OH H3C OH Руruvic Acid
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- Amino sequence: Gln-Glu-Val-Leu-Ile-Arg-Leu-Phe-Lys-Gly-His-Pro-Glu-Thr-Leu-Glu-Lys-Phe-Asp-Lys-Phe-Lys-His-Leu-Lys-Ser-Glu-Asp-Glu-Met-Lys-Ala-Ser-Glu-Asp-Leu-Lys A) List the fragments generated with trypsin: B) List the fragments generated with chymotrypsin (5 pts) (assume reaction conditions are used to maximize cutting to the C-terminal size of only the 3 aromatic amino acids.)Why does hematoxylin stain cartilage? ThanksIf phenylalanine was not an essential amino acid, would diet therapy (the elimination of phenylalanine from the diet) for PKU work?
- Human blood serum contains a class of enzymes known as acid phosphatases, which hydrolyze biological phosphate esters under slightly acidic conditions (pH 5.0): R-O-P-O3-2 + H2O --> R-OH + HO-P-O3-2. Acid phosphatases are produced by erythrocytes, the liver, kidney, spleen, and prostate gland. The enzyme from the prostate gland is clinically important because an increased activity in the blood is frequently an indication of cancer of the prostate gland. The phosphatase from the prostate gland is strongly inhibited by tartrate ion, but acid phosphatases from other tissues are not. How can this information be used to develop a commercial specific procedure for measuring the activity of the acid phosphatase of the prostate gland in human blood serum? * 1. Prostate cancer cannot be diagnosed biochemically. 2. Use tartrate to inhibit phosphatase from prostate gland and then subtract the results from the total serum enzyme activities to get an…Does sn enzyme undergo any net chemical change?If protein phosphatase 1 (PP1) is inhibited does Glycogen Synthase Kinase 3 become more active?
- What biochemical reaction is catalyzed by γ-secretase? Why was it proposed that a chemical inhibitor of this activity might be a useful drug for treating Alzheimer’s disease? What possible side effects of such a drug would complicate this use?Only do the following- synthesize a monoglyceride and diglycerides and attach them below. Make sure to identify which is which!The primary structure of b-endorphin, a peptide containing 31 amino acids synthesized by the body to control pain, is shown here: Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr- Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu What fragments are obtained as a result of treatment withcyanogen bromide?