The immediate effect of ADH on the renal tubules of frogs and mice is the same, yet when ADH is secreted, frogs produce urine that is approximately isosmotic to their blood plasma, whereas mice produce urine far more concentrated than their blood plasma. Explain this difference in terms of the factors affecting osmosis in the kidneys of frogs and mice.

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter15: Fluid And Acid-base Balance
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The immediate effect of ADH on the renal tubules of frogs and
mice is the same, yet when ADH is secreted, frogs produce urine
that is approximately isosmotic to their blood plasma, whereas
mice produce urine far more concentrated than their blood
plasma. Explain this difference in terms of the factors affecting
osmosis in the kidneys of frogs and mice.

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