The phenomenon of allelic exclusion ensures that B cells a. use only one V, D, and J segment during somatic recombination b. express only one type of heavy chain and one type of light chain c. do not undergo alternative splicing until cell proliferation commences d. do not secrete antibody until antigen is encountered e. carry out affinity maturation directed at heavy chains and not light chains f. derived from B-cell lymphomas are heterogeneous.

The phenomenon of allelic exclusion ensures that B cells a. use only one V, D, and J segment during somatic recombination b. express only one type of heavy chain and one type of light chain c. do not undergo alternative splicing until cell proliferation commences d. do not secrete antibody until antigen is encountered e. carry out affinity maturation directed at heavy chains and not light chains f. derived from B-cell lymphomas are heterogeneous.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter17: Genes And The Immune System

Section: Chapter Questions

Problem 14QP

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