The question, Explain the mechanism of the genotoxic agent invalidating the regulator and pathway

Q: please answer Why is it useful to have two different mechanisms of positive regulation? I.e. why…

A: The L-arabinose operon, also called the ara or araBAD operon, is an operon required for the…

Q: What inhibit CDK activity by bindingdirectly to the cyclin-CDK complex.

A: A cyclin-dependent kinase complex or CDKC or cyclin-CDK is formed by the interaction of a regulatory…

Q: Some of the mutations of the type mentioned in Problem 28 have an interesting property: they prevent…

A: Mutation is the sudden heritable changes that occur in the DNA sequences due to error while copying…

Q: d. What does ‘transfection’ mean? e. What are ‘single clones’ and how did various single clones…

A: de novo DNA methylation is the addition of methyl groups to specific sites in the promoter region of…

Q: How dynamics of cytoskeltol proteins is influenced by post translational modification. Name factors…

A: Cytoskeletal proteins are the proteins which interlink to make up the cytoskeleton of a cell. The…

Q: Understanding why these receptors are present when they are not supposed to be is important in…

A: When there is methylation at the cytosines present in promoter the genes are silenced as they blocks…

Q: Identify a Transcription Factor (TF) / DNA Regulatory Protein (DRP) that is functional in Humans…

A: Answer: Introduction: Eukaryotic cellular process is regulated in the transcription process and RNA…

Q: The similarity between Apc in colon cancers and Rb in retinoblastomas is that both are mutated in…

A: Answer) The similarity between APC in colon cancers and Rb in retinoblastomas is that both are…

Q: Histones : MOLECULAR BIOLOGY_advanced are basic proteins. carry an epigenetic code similar…

A: Histones are strongly alkaline proteins with a lot of lysine and arginine residue which are present…

Q: The effect of alternative splicing on RNAs and also on the function of tumor suppressor genes (TSG).…

A: Alternative splicing is an RNA molecule modification or splicing process that results in various…

Q: The retinoblastoma tumor suppressor gene Rb (RB1) codes forthe retinoblastoma protein (pRB). pRB…

A: Retinoblastoma is a tumor suppressor gene during cancer progression, loss of function of tumor…

Q: Lactose intolerant individuals do not produce the enzyme lactase. Studies show that the gene that…

A: Lactose sugar is obtained from milk products and milk. When people do not produce enough lactase…

Q: A certain nonsense suppressor corrects a nongrowingmutant to a state that is near, but not exactly,…

A: A nonsense suppressor mutation can influence the effects of nonsense mutations. It is usually a…

Q: Explain the main regulator being evaluated in the article histone h4 dosage modulates DNA damage…

A: In hospitals around the world, that is well stated that they are been defined as the Candida…

Q: Human papilloma virus (HPV) is present in greater than 90% of cervical cancers. HPV encodes two…

A: The E6 and E7 genes of the perilous human papillomavirus types encrypt oncoproteins and both act by…

Q: Explain about the mechanism of genotoxic agent in validating the regulator and pathway from article…

A: Candida glabrata, a nosocomial parasitic circulation system microbe, causes huge bleakness and…

Q: ''The chemical carcinogen dimethylbenz[a]anthra-cene (DMBA) must be an extraordinarily specific…

A: Abnormal growth of skin cells when exposed to sunlight causes skin cancer. They are originated from…

Q: HOW THE RECOMBINANT PROTEIN COULD BE EXPRESSED IN E. COLI 1. STRATEGIES TO IMPROVE THE PROTEIN…

A: Protein expression is a feature of DNA Recombinant technology or genetic engineering. Protein…

Q: True/False: When first discovered, investigators found it surprising that some single-gene defects…

A: Immunodeficiencies happen when at least one segments of the safe framework is faulty. The most…

Q: Azidothymidine is a Thymidine analog used to inhibit viral reverse transcriptase. Explain the…

A: AZT is a structural analogue of the deoxy thymidine. it was first synthesized in 1964. it failed as…

Q: In transcription Rho-dependent termination in bacteriophage is more common than in bacteria. True…

A: Transcription is defined as the synthesis of mRNA from the template strand of DNA. The RNA…

Q: The chromosome 9/22 translocation associated withCML (chronic myelogenous leukemia) is called…

A: The translocation of C-ABL gene into the BCR gene makes a BCR-ABL fusion gene which codes for an…

Q: The three stages of transcription (initiation, elongation, and termination) – with a focus on how…

A: Transcription is a process of production of of RNA from the DNA. It is also called the expression of…

Q: Effects of BPA on phosphorylation of JAK family in RAW264.7 cells

A:

Q: The mechanism by which lactose controls the lac of A) O Catabolite repression B) O DNA polymerase C)…

A: Operons are studied to understand the regulation of gene expression. It is studied under the domain…

Q: UDP , gemcitabine was shown to undergo two successive phosphorylations at . The product, gemcitabine…

A: GEMCITABINE is a chemotherapy medication, used to treat cancer such as breast cancer, testicular…

Q: 5-Azocytidine is an inhibitor of DNA methyltransferase. If thisdrug were fed to female mice during…

A: DNA methyltransferase is an enzyme, which is involved in the transfer of methyl group from the…

Q: RBBP6 variant 1 was found expressed throughout the cell division cycle

A: Since you have asked multiple question, we will solve the first question for you. If youwant any…

Q: Many transcription factors function as dimers. The binding sites of dimeric transcription factors…

A: In eukaryotes the transcription process relies on transcription factors (like general transcription…

Q: In addition to Tc1, the C. elegans genome contains otherfamilies of DNA transposons such as Tc2,…

A: Transposons are mobile DNA segments. They can replicate and insert copies at various chromosomal…

Q: If a cell cannot make any Rb protein, how will this affect the function of E2F?

A: Mutation in the deoxyribonucleic acid (DNA) can cause cancer. Abnormal and unnecessary growth of…

Q: "Schematic outline of melanogenesis. UVR stimulates the expression of POMC by keratinocytes. The…

A: Melanogenesis is the chemical pathway through which natural pigments known to be melanin pigments…

Q: The tumor suppressor pRB also binds to and suppresses the activity of retinoblastoma-binding protein…

A: Mutation in genes is the process of change in the nucleotide sequence of the genome.

Q: I-cell disease is a classic example of an inherited human defect in protein targeting that affects…

A: Lysosomes are membrane-bound organelles that house digestive enzymes. Lysosomes include…

Q: it and answer the following questions. Recent studies showing a correlation between the levels of…

A: Cytosine is one of the four nucleobases found in DNA and RNA, along with adenine, guanine, and…

Q: X31b is an experimental compound that is taken up by rapidly dividing cells. Research has shown that…

A: Cancer is a disorder in which abnormal cells divide irrepressibly and destroy the tissues of body.…

Q: Please answer all questions if possible.  -B-Raf is not overexpressed in cancer though shows…

A: B raf is a protooncogene that produce BRaf protein. This protein plays role in regulating MAP…

Q: Cell lysis and protein purification of GST-DHFR-His using T7 RNA polymerase protein to express DHFR…

A: A flowchart is a diagram that shows the steps of the process through a workflow which makes it…

Q: Negative supercoiling of DNA favors the transcription of genes because it facilitates unwinding.…

A: Transcription can be defined as the process in which RNA is formed from the DNA. This is the first…

Q: Effects of BPA on phosphorylation of MAPK family in RAW264.7 cells conclusion

A: Bisphenol A or BPA is one of the key component of polycarbonate plastics and it causes a wide range…

Q: Explain the mode of action of transcription inhibitor metarrestin. Explain why transcription…

A: Transcription is the process of formation of messenger RNA from DNA. It takes place inside the…

Q: Chromatin remodeling is linked to epigenetics.  Explain how this works and indicate the driving…

A: Epigenetics is referred to as the study of phenotype changes that are inheritable and does not…

Q: Some of the mutations of the type have an interesting property: they prevent the formation of the…

A: Attenuation is a method of transcription regulation which occurs after initiation of transcription.…

Q: Phosphorylation of elf-2 regulates eukaryotic protein synthesis initiation by inhibiting formation…

A: In mammalian cells, mRNA translation is continuous and one of the first mechanisms that control the…

Q: Effects of BPA on phosphorylation and translocation of NFκB and degradation of IκB in RAW264.7 cells…

A:

Q: HOW THE RECOMBINANT PROTEIN COULD BE EXPRESSED IN E. COLI 1. FACTORS AFFECTING BACTERIAL EXPRESSION…

A:

Q: why Penicillin inhibits PBP activity in wild-type cells

A: Penicillin is an antibiotic, which is derived from Penicilluim molds. It is used to fight against a…

Tissue regeneration & repair

Tissue regeneration involves the restoration of tissue components by regrowth of damaged tissues. In contrast, tissue repair involves patching of injured tissue rather than restoring it. It is the proliferative capacity of the cells that decides the amount of regeneration against the repair that would occur in the tissue. Both regeneration and repair depending on the duration of the injury and response to the inflammation.